Carbon nanotubes as assisted matrix for laser desorption/ionization time-of-flight mass spectrometry

	Carbon nanotubes as assisted matrix for laser desorption/ionization time-of-flight mass spectrometry
	Xu, SY ; Li, YF ; Zou, HF ; Qiu, JS ; Guo, Z ; Guo, BC
刊名	analytical chemistry
	2003-11-15
卷号	75 期号:22 页码:6191-6195
英文摘要	analysis of low molecular weight compounds with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tofms) has been developed by using carbon nanotubes obtained from coal by arc discharge as the matrix. the carbon nanotube matrix functions as substrate to trap analytes of peptides, organic compounds, and beta-cyclodextrin deposited on its surface. it has been found that carbon nanotubes can transfer energy to the analyte under laser irradiation, which makes analytes well desorbed/ionized, and the interference of intrinsic matrix ions can be eliminated. at the same time, the fragmentation of the analyte can be avoided. a good sensitivity and excellent reproducibility of the spectrum signals are achieved. it is believed that this work not only will open a new field for applications of carbon nanotubes, but also will offer a new technique for high-speed analysis of low molecular weight compounds in areas such as metabolism research and characterization of natural products.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, analytical
研究领域[WOS]	chemistry
关键词[WOS]	porous silicon ; surface ; molecules ; peptides ; proteins ; films
收录类别	SCI
语种	英语
WOS记录号	WOS:000186601500023
公开日期	2015-11-10
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/138305]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China 2.Dalian Univ Technol, Dept Mat Sci & Chem Engn, State Key Lab Mat Modificat, Dalian 116012, Peoples R China 3.Dalian Univ Technol, Dept Mat Sci & Chem Engn, Carbon Res Lab, Dalian 116012, Peoples R China 4.Cleveland State Univ, Dept Chem, Cleveland, OH 44115 USA
推荐引用方式 GB/T 7714	Xu, SY,Li, YF,Zou, HF,et al. Carbon nanotubes as assisted matrix for laser desorption/ionization time-of-flight mass spectrometry[J]. analytical chemistry,2003,75(22):6191-6195.
APA	Xu, SY,Li, YF,Zou, HF,Qiu, JS,Guo, Z,&Guo, BC.(2003).Carbon nanotubes as assisted matrix for laser desorption/ionization time-of-flight mass spectrometry.analytical chemistry,75(22),6191-6195.
MLA	Xu, SY,et al."Carbon nanotubes as assisted matrix for laser desorption/ionization time-of-flight mass spectrometry".analytical chemistry 75.22(2003):6191-6195.