Hydrogels assembled from star-shaped polypeptides with a dendrimer as the core

	Hydrogels assembled from star-shaped polypeptides with a dendrimer as the core
	Shen, Yong 1; Zhang, Shusheng 1; Wan, Yaoming 1; Fu, Wenxin 1; Li, Zhibo 1,2
刊名	SOFT MATTER
	2015
卷号	11 期号:15 页码:2945-2951
英文摘要	A second or fourth generation dendrimer with primary amine as the peripheral terminal group was first synthesized via Michael addition and thiol-yne addition. A series of star-shaped polypeptides was synthesized by ring opening polymerization (ROP) of gamma-(2-(2-methoxyethoxy)ethyl) L-glutamate (L-EG(2)Glu) N-carboxyanhydride (NCA) using the amine group terminated dendrimer as the initiator. Taking advantage of the well-defined dendrimer and ROP, the arm number and arm length can be easily controlled. These star-shaped poly(L-EG(2)Glu) can spontaneously form hydrogels instead of micelles in water at low concentration. The critical gelation concentration (CGC) and hydrogel strength displayed a stronger dependence on arm numbers than the arm length under similar conditions. These properties can be easily modulated by varying the poly(L-EG(2)Glu) arm length and arm number. The hydrogels showed shear thinning and rapid recovery properties. TEM and AFM characterization revealed that the hydrogel networks were constituted by entangled and branched fibrils.
收录类别	SCI
语种	英语
公开日期	2015-11-03
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/28507]
专题	化学研究所_高分子物理与化学实验室
作者单位	1.Chinese Acad Sci, Inst Chem, Lab Polymer Phys & Chem, Beijing 100190, Peoples R China 2.Qingdao Univ Sci & Technol, Sch Polymer Sci & Engn, Qingdao 266042, Peoples R China
推荐引用方式 GB/T 7714	Shen, Yong,Zhang, Shusheng,Wan, Yaoming,et al. Hydrogels assembled from star-shaped polypeptides with a dendrimer as the core[J]. SOFT MATTER,2015,11(15):2945-2951.
APA	Shen, Yong,Zhang, Shusheng,Wan, Yaoming,Fu, Wenxin,&Li, Zhibo.(2015).Hydrogels assembled from star-shaped polypeptides with a dendrimer as the core.SOFT MATTER,11(15),2945-2951.
MLA	Shen, Yong,et al."Hydrogels assembled from star-shaped polypeptides with a dendrimer as the core".SOFT MATTER 11.15(2015):2945-2951.