The asymmetric membrane structure of erythrocytes from Crucian carp studied by atomic force microscopy

	The asymmetric membrane structure of erythrocytes from Crucian carp studied by atomic force microscopy
	Tian, Yong-Mei ; Cai, Ming-Jun ; Zhao, Wei-Dong ; Wang,Shao-Wen ; Qin,Qi-Wei ; Wang,Hong-Da
刊名	科学通报(英文版) chinese science bulletin
	2014
卷号	59 期号:21 页码:2582-2587
关键词	CELL-MEMBRANES AFM PROTEINS RECEPTOR RAFTS
通讯作者	wang,hd
英文摘要	cell membranes play a key role in cellular activities. fish erythrocytes, prototype of the nucleated erythrocytes of lower vertebrates, are predominantly oval, biconvex discs with elliptical nucleus and much larger in size than human erythrocytes. in attempts to disclose the correlation of membrane structure between fish and human erythrocytes, we used in situ atomic force microscope (afm) combined with single-molecule force spectroscopy to study the membrane structure of crucian carp erythrocytes under quasi-native conditions. our results revealed the asymmetric distribution of proteins in crucian carp erythrocyte membrane: the outer leaflet of membrane is rather smooth without any proteins, whereas the inner leaflet of membrane is very rough with dense proteins. the asymmetry of fish erythrocyte membrane structure fits well with the semi-mosaic model of human erythrocyte membrane structure. this similarity of membrane structure between human and fish erythrocytes extends the semi-mosaic model of erythrocytes membrane structure to a wider range of species.
收录类别	SCI
语种	英语
公开日期	2015-10-27
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/57507]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Tian, Yong-Mei,Cai, Ming-Jun,Zhao, Wei-Dong,et al. The asymmetric membrane structure of erythrocytes from Crucian carp studied by atomic force microscopy[J]. 科学通报(英文版) chinese science bulletin,2014,59(21):2582-2587.
APA	Tian, Yong-Mei,Cai, Ming-Jun,Zhao, Wei-Dong,Wang,Shao-Wen,Qin,Qi-Wei,&Wang,Hong-Da.(2014).The asymmetric membrane structure of erythrocytes from Crucian carp studied by atomic force microscopy.科学通报(英文版) chinese science bulletin,59(21),2582-2587.
MLA	Tian, Yong-Mei,et al."The asymmetric membrane structure of erythrocytes from Crucian carp studied by atomic force microscopy".科学通报(英文版) chinese science bulletin 59.21(2014):2582-2587.