Red-to-blue colorimetric detection of cysteine via anti-etching of silver nanoprisms

CORC > 宁波材料技术与工程研究所 > 中国科学院宁波材料技术与工程研究所 > 2014专题

	Red-to-blue colorimetric detection of cysteine via anti-etching of silver nanoprisms
	Li, Yonglong ; Li, Zihou ; Gao, Yuexia ; Gong, An ; Zhang, Yujie ; Hosmane, Narayan S. ; Shen, Zheyu ; Wu, Aiguo
刊名	NANOSCALE
	2014
卷号	6 期号:18 页码:10631
中文摘要	The reported strategies for cysteine (Cys) colorimetric detection based on noble metal nanomaterials include triggering aggregation, etching or fluorescence quenching of nanomaterials by Cys. In this study, we propose a new strategy for Cys colorimetric detection, i.e. anti-etching of silver nanoprisms (AgNPRs). In the absence of Cys, iodide ions (I-) could etch the corners and edges of AgNPRs and induce the morphology transition from nanoprism to nanodisk, which results in color change of the AgNPR dispersion from blue to red. In its presence, however, Cys can prevent the AgNPRs from I- attack. In that case, the color of the AgNPR dispersion containing I- and Cys remains blue. The mechanism is confirmed by using UV-vis spectra, TEM, DLS, Raman spectra and XPS spectra. According to the sensing effect of the Cys detection system, the concentration of I- incubated with AgNPRs, incubation time of AgNPRs and I- , and pH of AgNPR dispersions are optimized to 5.0 mu M, 10 min, and pH 6.2, respectively. Under the optimized conditions, the proposed Cys detection system has excellent selectivity and high sensitivity. The limit of detection (LOD) of our Cys detection system is 25 nM by the naked eye, which is much better than the reported lowest LOD by eye-vision (100 nM), and 10 nM by UV-vis spectroscopy. The results of Cys detection in rabbit urine or plasma samples reinforce that our Cys detection system is applicable for rapid colorimetric detection of Cys in real body fluid samples.
公开日期	2015-09-20
内容类型	期刊论文
源URL	[http://ir.nimte.ac.cn/handle/174433/12001]
专题	宁波材料技术与工程研究所_2014专题
推荐引用方式 GB/T 7714	Li, Yonglong,Li, Zihou,Gao, Yuexia,et al. Red-to-blue colorimetric detection of cysteine via anti-etching of silver nanoprisms[J]. NANOSCALE,2014,6(18):10631.
APA	Li, Yonglong.,Li, Zihou.,Gao, Yuexia.,Gong, An.,Zhang, Yujie.,...&Wu, Aiguo.(2014).Red-to-blue colorimetric detection of cysteine via anti-etching of silver nanoprisms.NANOSCALE,6(18),10631.
MLA	Li, Yonglong,et al."Red-to-blue colorimetric detection of cysteine via anti-etching of silver nanoprisms".NANOSCALE 6.18(2014):10631.