Protection by Vanadium, a Contemporary Treatment Approach to Both Diabetes and Focal Cerebral Ischemia in Rats

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	Protection by Vanadium, a Contemporary Treatment Approach to Both Diabetes and Focal Cerebral Ischemia in Rats
	Liu, Zhenquan 2; Li, Pengtao 2; Zhao, Dan 2; Tang, Huiling 2; Guo, Jianyou1
刊名	BIOLOGICAL TRACE ELEMENT RESEARCH
	2012
卷号	145 期号:1 页码:66-70
关键词	Vanadium Diabetes Focal cerebral ischemia Insulin Cerebrovascular disease
ISSN号	0163-4984
通讯作者	Guo, JY (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China.
产权排序	2
英文摘要	There is now substantial epidemiological evidence that diabetes is a risk factor for cerebrovascular disease. The protection by vanadium from focal cerebral ischemia in diabetic rats was studied in this paper. Rats with streptozotocin-induced diabetes were subjected to middle cerebral artery occlusion followed by 4 weeks of administration of 0.6 mg/ml sodium orthovanadate in drinking water. Vanadium significantly improved the outcome in diabetic rats after cerebral ischemia and reperfusion in terms of neurobehavioral function. Vanadium reduces brain damage in streptozotocin-induced diabetic rats by imitating action of insulin.
学科主题	Medical psychology
收录类别	SCI
项目简介	This work was supported by the Key New Drugs Innovation project from Ministry of Science and Technology (2009ZX09502-017), Program for New Century Excellent Talents in University (NCET-10-0273), Beijing Nova Program (2010B035), the project from Key Laboratory of Mental Health, Chinese Academy of Sciences, Young Scientist project from IPCAS (08CX043004), NNSF grant (30800301), and the Knowledge Innovation Program of the Chinese Academy of Sciences (KSCX2-YW-R-254, KSCX2-EW-Q-18 and KSCX2-EW-J-8).
原文出处	http://download.springer.com/static/pdf/5/art%253A10.1007%252Fs12011-011-9168-9.pdf?auth66=1426580207_3a014d8b6bc884094f98594ed04be4a6&ext=.pdf
语种	英语
WOS记录号	WOS:000299090300009
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/12906]
专题	心理研究所_中国科学院心理健康重点实验室
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Beijing Univ Chinese Med, Sch Basic Med Sci, Beijing 100102, Peoples R China
推荐引用方式 GB/T 7714	Liu, Zhenquan,Li, Pengtao,Zhao, Dan,et al. Protection by Vanadium, a Contemporary Treatment Approach to Both Diabetes and Focal Cerebral Ischemia in Rats[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2012,145(1):66-70.
APA	Liu, Zhenquan,Li, Pengtao,Zhao, Dan,Tang, Huiling,&Guo, Jianyou.(2012).Protection by Vanadium, a Contemporary Treatment Approach to Both Diabetes and Focal Cerebral Ischemia in Rats.BIOLOGICAL TRACE ELEMENT RESEARCH,145(1),66-70.
MLA	Liu, Zhenquan,et al."Protection by Vanadium, a Contemporary Treatment Approach to Both Diabetes and Focal Cerebral Ischemia in Rats".BIOLOGICAL TRACE ELEMENT RESEARCH 145.1(2012):66-70.