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	Indole alkaloids with antibacterial activity from aqueous fraction of Alstonia scholaris
	Qin, Xu-Jie1,2; Zhao, Yun-Li1; Lunga, Paul-Keilah1; Yang, Xing-Wei1; Song, Chang-Wei1; Cheng, Gui-Guang1; Liu, Lu1,2; Chen, Ying-Ying1,2; Liu, Ya-Ping1; Luo, Xiao-Dong1
刊名	TETRAHEDRON
	2015-06-24
卷号	71期号:25页码:4372-4378
关键词	Apocynaceae Alstonia scholaris Indole alkaloid Antibacterial activity
通讯作者	Liu,YP (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Yunnan,Peoples R China. ; liuyaping@mail.kib.ac.cn ; xdluo@mail.kib.ac.cn
英文摘要	Eleven new indole alkaloids, alstoniascholarines A-K (1-11), along with one known analogue, were isolated from the aqueous fraction of Alstonia scholaris leaf extract. Their structures were established on the basis of extensive spectroscopic data analysis, chemical transformation, and quantum theory. Alkaloid 4 possessed a novel skeleton with fused-ring and a six-membered ring, the absolute configuration of which was assigned by quantum theory. Alkaloids 6 and 10 showed the best antibacterial activity against Pseudomonas aeruginosa with an MIC value of 3.13 mu g/mL. (C) 2015 Elsevier Ltd. All rights reserved.
学科主题	Chemistry, Organic
类目[WOS]	Chemistry, Organic
研究领域[WOS]	Chemistry
关键词[WOS]	FLIGHT MASS-SPECTROMETRY ; LEAVES ; ACID ; IDENTIFICATION ; EXTRACT
收录类别	SCI
语种	英语
WOS记录号	WOS:000356111100012
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/21337]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Qin, Xu-Jie,Zhao, Yun-Li,Lunga, Paul-Keilah,et al. Indole alkaloids with antibacterial activity from aqueous fraction of Alstonia scholaris[J]. TETRAHEDRON,2015,71(25):4372-4378.
APA	Qin, Xu-Jie.,Zhao, Yun-Li.,Lunga, Paul-Keilah.,Yang, Xing-Wei.,Song, Chang-Wei.,...&Luo, Xiao-Dong.(2015).Indole alkaloids with antibacterial activity from aqueous fraction of Alstonia scholaris.TETRAHEDRON,71(25),4372-4378.
MLA	Qin, Xu-Jie,et al."Indole alkaloids with antibacterial activity from aqueous fraction of Alstonia scholaris".TETRAHEDRON 71.25(2015):4372-4378.

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