Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii

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	Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii
	Zhang, Peng1,2 ; Li, Xiao-Ming 1; Wang, Jia-Ning1,2 ; Li, Xin1,2 ; Wang, Bin-Gui1
刊名	CHINESE CHEMICAL LETTERS
	2015-03-01
卷号	26 期号:3 页码:313-316
关键词	Natural products Indolediketopiperazine Marine algal-derived fungus Paecilomyces variotii Cytotoxicity
英文摘要	Two new prenylated indole alkaloids, namely, dihydrocarneamide A (1) and iso-notoamide B (2), were isolated from the marine-derived endophytic fungus Paecilomyces variotii EN-291. The structures of these metabolites were determined based on comprehensive spectral analysis, together with chiral HPLC analysis of the acidic hydrolysates. Unlike other prenylated indole alkaloids such as asperparalines, notoamides, and versicolamides, compounds 1 and 2 are the rare examples of C-5 prenylation, forming the fused dimethyldihydropyran ring at C-5 and C-6 of the indole ring. The cytotoxic activity of the isolated compounds was evaluated. (C) 2014 Bin-Gui Wang. Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. All rights reserved.
收录类别	SCI
语种	英语
WOS记录号	WOS:000353089000012
公开日期	2015-06-16
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/25484]
专题	海洋研究所_实验海洋生物学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Peng,Li, Xiao-Ming,Wang, Jia-Ning,et al. Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii[J]. CHINESE CHEMICAL LETTERS,2015,26(3):313-316.
APA	Zhang, Peng,Li, Xiao-Ming,Wang, Jia-Ning,Li, Xin,&Wang, Bin-Gui.(2015).Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii.CHINESE CHEMICAL LETTERS,26(3),313-316.
MLA	Zhang, Peng,et al."Prenylated indole alkaloids from the marine-derived fungus Paecilomyces variotii".CHINESE CHEMICAL LETTERS 26.3(2015):313-316.