Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum | |
Liu, Hong-Xin1,2,3,4; Tan, Hai-Bo3; He, Meng-Ting5; Li, Ling5; Wang, Yue-Hu1,2; Long, Chun-Lin1,2,6 | |
刊名 | TETRAHEDRON |
2015-04-22 | |
卷号 | 71期号:16页码:2369-2375 |
关键词 | Piper nudibaccatum ortho-alkylation Nudibaccatumin A Nudibaccatumin B |
通讯作者 | Wang,YH (reprint author),Chinese Acad Sci,Key Lab Econ Plants & Biotechnol,Kunming Inst Bot,Kunming 650201,Peoples R China. ; wan-gyuehu@mail.kib.ac.cn ; long@mail.kib.ac.cn |
英文摘要 | Two hydroxychavicol heterodimers comprising phenylpropanoid and monoterpene constituent units, named nudibaccatumins A (1) and B (2), were isolated as an inseparable mixture from the aerial parts of Piper nudibaccatum. Their absolute configurations were confirmed by total synthesis using ortho-alkylation of hydroxychavicol with myrtenyl bromide as the key reaction. The two new compounds (1 and 2) and their synthetic analogues (3-8) were evaluated for XO inhibitory activity. (C) 2015 Elsevier Ltd. All rights reserved. |
学科主题 | Chemistry, Organic |
类目[WOS] | Chemistry, Organic |
研究领域[WOS] | Chemistry |
关键词[WOS] | XANTHINE-OXIDASE ; PHYTOCHEMISTRY |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000352668900005 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn/handle/151853/19370] |
专题 | 昆明植物研究所_资源植物与生物技术所级重点实验室 |
作者单位 | 1.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming Inst Bot, Kunming 650201, Peoples R China 2.Chinese Acad Sci, Yunnan Key Lab Wild Plant Resources, Kunming Inst Bot, Kunming 650201, Peoples R China 3.Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China 4.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 5.Kunming Med Univ, Biomed Engn Res Ctr, Kunming 650500, Peoples R China 6.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, Hong-Xin,Tan, Hai-Bo,He, Meng-Ting,et al. Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum[J]. TETRAHEDRON,2015,71(16):2369-2375. |
APA | Liu, Hong-Xin,Tan, Hai-Bo,He, Meng-Ting,Li, Ling,Wang, Yue-Hu,&Long, Chun-Lin.(2015).Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum.TETRAHEDRON,71(16),2369-2375. |
MLA | Liu, Hong-Xin,et al."Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum".TETRAHEDRON 71.16(2015):2369-2375. |
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