Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum
Liu, Hong-Xin1,2,3,4; Tan, Hai-Bo3; He, Meng-Ting5; Li, Ling5; Wang, Yue-Hu1,2; Long, Chun-Lin1,2,6
刊名TETRAHEDRON
2015-04-22
卷号71期号:16页码:2369-2375
关键词Piper nudibaccatum ortho-alkylation Nudibaccatumin A Nudibaccatumin B
通讯作者Wang,YH (reprint author),Chinese Acad Sci,Key Lab Econ Plants & Biotechnol,Kunming Inst Bot,Kunming 650201,Peoples R China. ; wan-gyuehu@mail.kib.ac.cn ; long@mail.kib.ac.cn
英文摘要Two hydroxychavicol heterodimers comprising phenylpropanoid and monoterpene constituent units, named nudibaccatumins A (1) and B (2), were isolated as an inseparable mixture from the aerial parts of Piper nudibaccatum. Their absolute configurations were confirmed by total synthesis using ortho-alkylation of hydroxychavicol with myrtenyl bromide as the key reaction. The two new compounds (1 and 2) and their synthetic analogues (3-8) were evaluated for XO inhibitory activity. (C) 2015 Elsevier Ltd. All rights reserved.
学科主题Chemistry, Organic
类目[WOS]Chemistry, Organic
研究领域[WOS]Chemistry
关键词[WOS]XANTHINE-OXIDASE ; PHYTOCHEMISTRY
收录类别SCI
语种英语
WOS记录号WOS:000352668900005
内容类型期刊论文
源URL[http://ir.kib.ac.cn/handle/151853/19370]  
专题昆明植物研究所_资源植物与生物技术所级重点实验室
作者单位1.Chinese Acad Sci, Key Lab Econ Plants & Biotechnol, Kunming Inst Bot, Kunming 650201, Peoples R China
2.Chinese Acad Sci, Yunnan Key Lab Wild Plant Resources, Kunming Inst Bot, Kunming 650201, Peoples R China
3.Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China
4.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
5.Kunming Med Univ, Biomed Engn Res Ctr, Kunming 650500, Peoples R China
6.Minzu Univ China, Coll Life & Environm Sci, Beijing 100081, Peoples R China
推荐引用方式
GB/T 7714
Liu, Hong-Xin,Tan, Hai-Bo,He, Meng-Ting,et al. Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum[J]. TETRAHEDRON,2015,71(16):2369-2375.
APA Liu, Hong-Xin,Tan, Hai-Bo,He, Meng-Ting,Li, Ling,Wang, Yue-Hu,&Long, Chun-Lin.(2015).Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum.TETRAHEDRON,71(16),2369-2375.
MLA Liu, Hong-Xin,et al."Isolation and synthesis of two hydroxychavicol heterodimers from Piper nudibaccatum".TETRAHEDRON 71.16(2015):2369-2375.
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