Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue

	Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue
	Wang, Xueqin 1,2; Xing, Ronge1 ; Chen, Zuoyuan 3; Yu, Huahua1 ; Li, Rongfeng 1; Li, Pengcheng1
刊名	FOOD & FUNCTION
	2014-09-01
卷号	5 期号:9 页码:2113-2119
通讯作者	Wang, XQ (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China.
英文摘要	Mackerel protein hydrolysate (MPH) was purified through ultrafiltration membranes, and its effect and mechanism for anti-fatigue were investigated in mice. The result showed that MPH (<2.5 kDa) had effective free radical scavenging activities. Moreover, the MPH groups could significantly prolong exhaustion swimming time compared to the normal and other groups. The liver glycogen level was markedly increased by 33-35% and the BUN (16-17%), LA (14-19%) and MDA (16-31%) levels were decreased in the MPH group compared to that of the control group. In addition, MPH improved enzymatic antioxidant system by increasing the activities of SOD and GSH-Px. This study exhibited possible anti-fatigue mechanism of MPH, as follows: first, the MPH could supplement the concentration of blood glycogen and eliminate metabolites, which were related to fatigue; second, MPH with free radical scavenging ability could enhance the activities of antioxidant enzymes, which could alleviate fatigue.
学科主题	Biochemistry & Molecular Biology; Food Science & Technology
收录类别	SCI
语种	英语
WOS记录号	WOS:000341016500013
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/24206]
专题	海洋研究所_海洋生物技术研发中心海洋研究所_海洋环境工程技术研究发展中心
作者单位	1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Univ Med Coll, Affiliated Hosp Qingdao, Dept Cardiol, Qingdao 266003, Peoples R China
推荐引用方式 GB/T 7714	Wang, Xueqin,Xing, Ronge,Chen, Zuoyuan,et al. Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue[J]. FOOD & FUNCTION,2014,5(9):2113-2119.
APA	Wang, Xueqin,Xing, Ronge,Chen, Zuoyuan,Yu, Huahua,Li, Rongfeng,&Li, Pengcheng.(2014).Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue.FOOD & FUNCTION,5(9),2113-2119.
MLA	Wang, Xueqin,et al."Effect and mechanism of mackerel (Pneumatophorus japonicus) peptides for anti-fatigue".FOOD & FUNCTION 5.9(2014):2113-2119.