Fabricating a Cycloolefin Polymer Immunoassay Platform with a Dual-Function Polymer Brush via a Surface-Initiated Photoiniferter-Mediated Polymerization Strategy

	Fabricating a Cycloolefin Polymer Immunoassay Platform with a Dual-Function Polymer Brush via a Surface-Initiated Photoiniferter-Mediated Polymerization Strategy
	Ma, Jiao ; Luan, Shifang ; Song, Lingjie ; Jin,Jing ; Yuan,Shuaishuai ; Yan,Shunjie ; Yang,Huawei ; Shi,Hengchong ; Yin,Jinghua
刊名	acs applied materials & interfaces
	2014
卷号	6 期号:3 页码:1971-1978
关键词	TRANSFER RADICAL POLYMERIZATION ANTI-FOULING SURFACES ZWITTERIONIC POLYMER COVALENT FUNCTIONALIZATION BIOLOGICAL APPLICATIONS PROTEIN ADSORPTION ACTIVE PROTEINS CELL-ADHESION BLOOD-PLASMA IMMOBILIZATION
通讯作者	luan,sf
英文摘要	the development of technologies for a biomedical detection platform is critical to meet the global challenges of various disease diagnoses. in this study, an inert cycloolefin polymer (cop) support was modified with two-layer polymer brushes possessing dual functions, i.e., a low fouling poly[poly(ethylene glycol) methacrylate] [p-(pegma)] bottom layer and a poly(acrylic acid) (paa) upper layer for antibody loading, via a surface-initiated photoiniferter-mediated polymerization strategy for fluorescence-based immunoassay. it was demonstrated through a confocal laser scanner that, for the as-prepared cop-g-peg-b-paa-igg supports, nonspecific protein adsorption was suppressed, and the resistance to nonspecific protein interference on antigen recognition was significantly improved, relative to the cop-g-paa-igg references. this strategy for surface modification of a polymeric platform is also applicable to the fabrication of other biosensors.
收录类别	SCI
语种	英语
WOS记录号	WOS:000331493200083
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/52355]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Ma, Jiao,Luan, Shifang,Song, Lingjie,et al. Fabricating a Cycloolefin Polymer Immunoassay Platform with a Dual-Function Polymer Brush via a Surface-Initiated Photoiniferter-Mediated Polymerization Strategy[J]. acs applied materials & interfaces,2014,6(3):1971-1978.
APA	Ma, Jiao.,Luan, Shifang.,Song, Lingjie.,Jin,Jing.,Yuan,Shuaishuai.,...&Yin,Jinghua.(2014).Fabricating a Cycloolefin Polymer Immunoassay Platform with a Dual-Function Polymer Brush via a Surface-Initiated Photoiniferter-Mediated Polymerization Strategy.acs applied materials & interfaces,6(3),1971-1978.
MLA	Ma, Jiao,et al."Fabricating a Cycloolefin Polymer Immunoassay Platform with a Dual-Function Polymer Brush via a Surface-Initiated Photoiniferter-Mediated Polymerization Strategy".acs applied materials & interfaces 6.3(2014):1971-1978.