Applications of direct methods in protein crystallography for dealing with diffraction data down to 5 A resolution

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	Applications of direct methods in protein crystallography for dealing with diffraction data down to 5 A resolution
	Fan, HF ; Gu, YX ; He, Y ; Lin, ZJ ; Wang, JW ; Yao, DQ ; Zhang, T
刊名	ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES
	2014
卷号	70 页码:239
ISSN号	0108-7673
通讯作者	Fan, HF (reprint author), Chinese Acad Sci, Inst Phys, Beijing 100190, Peoples R China.
中文摘要	Apart from solving the heavy-atom substructure in proteins and ab initio phasing of protein diffraction data at atomic resolution, direct methods have also been successfully combined with other protein crystallographic methods in dealing with diffraction data far below atomic resolution, leading to significantly improved results. In this respect, direct methods provide phase constraints in reciprocal space within a dual-space iterative framework rather than solve the phase problem independently. Applications of this type of direct methods to difficult SAD phasing, model completion and low-resolution phase extension will be described in detail. (C) 2014 International Union of Crystallography
资助信息	Chinese Academy of Sciences; 973 Project of the Ministry of Science and Technology of China [2002CB713801]
语种	英语
公开日期	2015-04-14
内容类型	期刊论文
源URL	[http://ir.iphy.ac.cn/handle/311004/58800]
专题	物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文
推荐引用方式 GB/T 7714	Fan, HF,Gu, YX,He, Y,et al. Applications of direct methods in protein crystallography for dealing with diffraction data down to 5 A resolution[J]. ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES,2014,70:239.
APA	Fan, HF.,Gu, YX.,He, Y.,Lin, ZJ.,Wang, JW.,...&Zhang, T.(2014).Applications of direct methods in protein crystallography for dealing with diffraction data down to 5 A resolution.ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES,70,239.
MLA	Fan, HF,et al."Applications of direct methods in protein crystallography for dealing with diffraction data down to 5 A resolution".ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 70(2014):239.