Excellent antimicrobial properties of silver-loaded mesoporous silica SBA-15

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 城市与区域生态国家重点实验室

	Excellent antimicrobial properties of silver-loaded mesoporous silica SBA-15
	Wang, L. ; He, H. ; Zhang, C. ; Sun, L. ; Liu, S. ; Yue, R.
刊名	JOURNAL OF APPLIED MICROBIOLOGY
	2014
卷号	116 期号:5 页码:1106-1118
关键词	E.coli reactive oxygen species antimicrobial activity SBA-15 silver
ISSN号	1364-5072
中文摘要	Aims To synthesize silver-loaded mesoporous silica SBA-15 (Ag/SBA-15) materials and examine their antimicrobial action and antimicrobial mechanism. Methods and Results Ag/SBA-15 materials were prepared by means of incipient wetness impregnation, impregnation and direct hydrothermal synthesis methods. The antimicrobial activity of Ag/SBA-15 was investigated using Escherichia coli as an indicator bacterium, and the antimicrobial mechanism was explored. The properties and Ag+ release behaviour of Ag/SBA-15 materials were compared. Experimental results showed that Ag/SBA-15 materials resulted in 7 center dot 5 log inactivation of E.coli for only 60min, which exhibited very high antimicrobial activities at room temperature without using any light or electrical power input. The cell wall and cell membrane were destroyed in the antimicrobial process, leading to leakage of intracellular components. The formation of extracellular reactive oxygen species (ROS) involved in the bactericidal process was confirmed. Production of intracellular ROS was also discovered. Conclusions Ag/SBA-15 exhibited high antimicrobial activity against E.coli. This antimicrobial effect was a synergistic action between extracellular ROS and the toxicity of Ag+, which induced intracellular ROS production and subsequent cell death. Significance and Impact of the Study This study revealed for the first time the antimicrobial activities and mechanisms of Ag/SBA-15 materials prepared with different methods.
WOS记录号	WOS:000334062400004
公开日期	2015-03-23
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/9158]
专题	生态环境研究中心_城市与区域生态国家重点实验室
推荐引用方式 GB/T 7714	Wang, L.,He, H.,Zhang, C.,et al. Excellent antimicrobial properties of silver-loaded mesoporous silica SBA-15[J]. JOURNAL OF APPLIED MICROBIOLOGY,2014,116(5):1106-1118.
APA	Wang, L.,He, H.,Zhang, C.,Sun, L.,Liu, S.,&Yue, R..(2014).Excellent antimicrobial properties of silver-loaded mesoporous silica SBA-15.JOURNAL OF APPLIED MICROBIOLOGY,116(5),1106-1118.
MLA	Wang, L.,et al."Excellent antimicrobial properties of silver-loaded mesoporous silica SBA-15".JOURNAL OF APPLIED MICROBIOLOGY 116.5(2014):1106-1118.