Hybrid polymer micelles capable of cRGD targeting and pH-triggered surface charge conversion for tumor selective accumulation and promoted uptake

	Hybrid polymer micelles capable of cRGD targeting and pH-triggered surface charge conversion for tumor selective accumulation and promoted uptake
	Hu, Xiuli ; Guan, Xingang ; Li, Jing ; Pei,Qing ; Liu,Ming ; Xie,Zhigang ; Jing,Xiabin
刊名	chemical communications
	2014
卷号	50 期号:65 页码:9788-9191
关键词	DRUG-DELIVERY SIRNA DELIVERY NANOPARTICLES HYPOXIA GLIOBLASTOMA DOXORUBICIN EFFICIENT POLYPLEX THERAPY SYSTEM
ISSN号	1359-7345
通讯作者	xie,zg
中文摘要	this study presents both tumor-targeting ligands (crgd) and ph-activated surface charge-conversional moiety (imidazole) decorated micelles for dox delivery. crgd is expected to induce preferential tumor accumulation, while imidazole switches on positive charge in a tumor acid environment, which leads to enhanced micelle uptake by tumor cells.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000339930400041
公开日期	2015-03-30
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/50742]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Hu, Xiuli,Guan, Xingang,Li, Jing,et al. Hybrid polymer micelles capable of cRGD targeting and pH-triggered surface charge conversion for tumor selective accumulation and promoted uptake[J]. chemical communications,2014,50(65):9788-9191.
APA	Hu, Xiuli.,Guan, Xingang.,Li, Jing.,Pei,Qing.,Liu,Ming.,...&Jing,Xiabin.(2014).Hybrid polymer micelles capable of cRGD targeting and pH-triggered surface charge conversion for tumor selective accumulation and promoted uptake.chemical communications,50(65),9788-9191.
MLA	Hu, Xiuli,et al."Hybrid polymer micelles capable of cRGD targeting and pH-triggered surface charge conversion for tumor selective accumulation and promoted uptake".chemical communications 50.65(2014):9788-9191.