Room temperature friction and wear of Ti₃SiC₂-Ag sliding against Inconel 718 with a hemisphere-on-disc configuration were investigated in air. The effects of Ag content and TiAlN coating on Inconel 718 substrate were also included. Ti₃SiC₂/Inconel 718 tribo-pair showed high friction coefficient (0.6) and severe wear due to pullout of Ti₃SiC₂ grains was observed at a sliding speed of 1 m/s. Ti₃SiC₂-Ag composites had better tribological behavior than that of monolithic Ti₃SiC₂ in sliding against Inconel 718. At a sliding speed of 0.01 m/s, Ti₃SiC₂-Ag/Inconel 718 tribo-pairs exhibited moderate friction coefficient (0.32-0.4). At a sliding speed of 1 m/s, severe wear was not observed for Ti₃SiC₂-15vol.%Ag and Ti₃SiC₂-20vol.%Ag composites although the tribo-layer was not rich in Ag. When Ti₃SiC₂-Ag composites mated with TiAlN coating on Inconel 718 substrate, moderate friction coefficient (0.29-0.36) and low wear rate (10^-6 mm³N^-1m^-1) were obtained at 0.01 m/s. A transition from mild wear to severe wear of Ti₃SiC₂-Ag composites at 0.1 m/s can be attributed to the ploughing effect by hard asperities on TiAlN coating.