4-CF3-ezetimibe analogs: design, synthesis, and biological evaluation of cholesterol absorption inhibitions

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	4-CF3-ezetimibe analogs: design, synthesis, and biological evaluation of cholesterol absorption inhibitions
	Liu YL(刘应乐) ; Chen JL(陈俊岭) ; Wang GH(王甘红) ; Sun P(孙鹏) ; Huang HY(黄贺瑶) ; Qing FL(卿凤翎)
刊名	Tetrahedron Lett.
	2013
卷号	54 期号:40 页码:5541-5543
ISSN号	0040-4039
其他题名	4-CF3-ezetimibe类似物: 分子设计，合成和胆固醇吸收的抑制生物学评价
通讯作者	卿凤翎
英文摘要	On the purpose of looking for better cholesterol absorption inhibitors, several trifluoromethyl substituted ezetimibe analogs 1a-d were designed and synthesized. The key steps in the synthesis of these optically pure trans-4-CF3-beta-lactams include chira
学科主题	氟化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1016/j.tetlet.2013.08.027
语种	英语
WOS记录号	WOS:000324452100030
公开日期	2014-10-15
内容类型	期刊论文
源URL	[http://ir.sioc.ac.cn/handle/331003/29229]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
推荐引用方式 GB/T 7714	Liu YL,Chen JL,Wang GH,et al. 4-CF3-ezetimibe analogs: design, synthesis, and biological evaluation of cholesterol absorption inhibitions[J]. Tetrahedron Lett.,2013,54(40):5541-5543.
APA	刘应乐,陈俊岭,王甘红,孙鹏,黄贺瑶,&卿凤翎.(2013).4-CF3-ezetimibe analogs: design, synthesis, and biological evaluation of cholesterol absorption inhibitions.Tetrahedron Lett.,54(40),5541-5543.
MLA	刘应乐,et al."4-CF3-ezetimibe analogs: design, synthesis, and biological evaluation of cholesterol absorption inhibitions".Tetrahedron Lett. 54.40(2013):5541-5543.