The impact of the number of layers of a graphene nanopore on DNA translocation | |
Lv, Wenping1; Chen, Maodu2; Wu, Ren'an1 | |
刊名 | soft matter |
2013 | |
卷号 | 9期号:3页码:960-966 |
通讯作者 | 吴仁安 |
产权排序 | 待补充 |
合作状况 | 英 |
英文摘要 | graphene nanopore based sensor devices have shown great potential for the detection of dna. to understand the fundamental aspects of dna translocation through a graphene nanopore, in this work, molecular dynamics (md) simulations and potential of mean force (pmf) calculations were carried out to investigate the impact of the number of graphene layers of small nanopores (2-3 nm) on dna translocation. it was observed that the ionic conductance was sensitive to the number of graphene layers of open-nanopores, and the probability of dna translocation through graphene nanopores was related to the thickness of the graphene nanopores. md simulations showed that dna translocation time was most sensitive to the thickness of graphene nanopores of 2.4 nm aperture, and the observed free energy barrier of pmfs and the profile change revealed the increased retardation of dna translocation through bilayer graphene nanopores as compared to that through monolayer graphene nanopores. |
学科主题 | 物理化学 |
WOS标题词 | science & technology ; physical sciences ; technology |
类目[WOS] | chemistry, physical ; materials science, multidisciplinary ; physics, multidisciplinary ; polymer science |
研究领域[WOS] | chemistry ; materials science ; physics ; polymer science |
关键词[WOS] | molecular-dynamics ; synthetic nanopore ; nucleic-acids ; simulation ; water ; conductance ; complexes ; membrane ; polymer ; sensors |
收录类别 | SCI |
资助信息 | 1,1 |
原文出处 | 966 |
语种 | 英语 |
WOS记录号 | WOS:000312335500040 |
公开日期 | 2014-09-11 |
内容类型 | 期刊论文 |
源URL | [http://159.226.238.44/handle/321008/119600] |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Dalian Univ Technol, Sch Phys & Optoelect Technol, Dalian 116024, Peoples R China |
推荐引用方式 GB/T 7714 | Lv, Wenping,Chen, Maodu,Wu, Ren'an. The impact of the number of layers of a graphene nanopore on DNA translocation[J]. soft matter,2013,9(3):960-966. |
APA | Lv, Wenping,Chen, Maodu,&Wu, Ren'an.(2013).The impact of the number of layers of a graphene nanopore on DNA translocation.soft matter,9(3),960-966. |
MLA | Lv, Wenping,et al."The impact of the number of layers of a graphene nanopore on DNA translocation".soft matter 9.3(2013):960-966. |
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