Selective capture and fluorescent quantification of glycoproteins using aminophenylboronic acid functionalized mesoporous silica coated CdTe quantum dots

	Selective capture and fluorescent quantification of glycoproteins using aminophenylboronic acid functionalized mesoporous silica coated CdTe quantum dots
	Zhang, Wei 1,2; He, Xi-Wen 1,2; Yang, Ya-Qiong 1,2; Li, Wen-You 1,2; Zhang, Yu-Kui 1,2,3
刊名	journal of materials chemistry b
	2013
卷号	1 期号:3 页码:347-352
通讯作者	李文友
产权排序	待补充
合作状况	英
英文摘要	in this work, aminophenylboronic acid functionalized mesoporous silica coated cdte quantum dots (apba-coated qds) were synthesized and applied to the selective capture and fluorescent quantification of glycoproteins. the as-prepared apba-coated qds, relying on the interaction between apba and cis-diol containing structures, demonstrated excellent selectivity for the glycoproteins. their high surface area and apba-enriched silica matrixes give rise to faster binding kinetics and higher binding capacity for the glycoproteins, which further make them attractive for biomedical/chemical sensing applications. based on the fluorescent properties of the particles, the as-prepared apba-coated qds were successfully applied to the fluorescence quantification of glycoproteins. the present study provides a facile strategy to fabricate functionalized fluorescent materials and is of great significance for isolation and detection of glycoproteins in proteomics.
学科主题	物理化学
WOS标题词	science & technology ; technology
类目[WOS]	materials science, biomaterials
研究领域[WOS]	materials science
关键词[WOS]	lectin affinity ; enrichment ; chromatography ; glycosylation ; proteins
收录类别	SCI
资助信息	2，5
原文出处	352
语种	英语
WOS记录号	WOS:000314787400011
公开日期	2014-09-11
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/119459]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Nankai Univ, State Key Lab Med Chem Biol, Tianjin 300071, Peoples R China 2.Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Dalian 116011, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Wei,He, Xi-Wen,Yang, Ya-Qiong,et al. Selective capture and fluorescent quantification of glycoproteins using aminophenylboronic acid functionalized mesoporous silica coated CdTe quantum dots[J]. journal of materials chemistry b,2013,1(3):347-352.
APA	Zhang, Wei,He, Xi-Wen,Yang, Ya-Qiong,Li, Wen-You,&Zhang, Yu-Kui.(2013).Selective capture and fluorescent quantification of glycoproteins using aminophenylboronic acid functionalized mesoporous silica coated CdTe quantum dots.journal of materials chemistry b,1(3),347-352.
MLA	Zhang, Wei,et al."Selective capture and fluorescent quantification of glycoproteins using aminophenylboronic acid functionalized mesoporous silica coated CdTe quantum dots".journal of materials chemistry b 1.3(2013):347-352.