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	Aniquinazolines A-D, Four New Quinazolinone Alkaloids from Marine-Derived Endophytic Fungus Aspergillus nidulans
	An, Chun-Yan1,2; Li, Xiao-Ming1; Li, Chun-Shun1; Wang, Ming-Hui1,2; Xu, Gang-Ming1; Wang, Bin-Gui1; Wang, BG
刊名	MARINE DRUGS
	2013-07-01
卷号	11期号:7页码:2682-2694
关键词	mangrove endophytic fungus Aspergillus nidulans secondary metabolites bioactivity
ISSN号	1660-3397
通讯作者	Wang, BG
中文摘要	Four new quinazolinone alkaloids, namely, aniquinazolines A-D (1-4), were isolated and identified from the culture of Aspergillus nidulans MA-143, an endophytic fungus obtained from the leaves of marine mangrove plant Rhizophora stylosa. The structures of the new compounds were elucidated by spectroscopic analysis, and their absolute configurations were determined on the basis of chiral HPLC analysis of the acidic hydrolysates. The structure for 1 was confirmed by single-crystal X-ray diffraction analysis. All these compounds were examined for antibacterial and cytotoxic activity as well as brine shrimp (Artemia salina) lethality.
英文摘要	Four new quinazolinone alkaloids, namely, aniquinazolines A-D (1-4), were isolated and identified from the culture of Aspergillus nidulans MA-143, an endophytic fungus obtained from the leaves of marine mangrove plant Rhizophora stylosa. The structures of the new compounds were elucidated by spectroscopic analysis, and their absolute configurations were determined on the basis of chiral HPLC analysis of the acidic hydrolysates. The structure for 1 was confirmed by single-crystal X-ray diffraction analysis. All these compounds were examined for antibacterial and cytotoxic activity as well as brine shrimp (Artemia salina) lethality.
学科主题	Pharmacology & Pharmacy
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Chemistry, Medicinal
研究领域[WOS]	Pharmacology & Pharmacy
关键词[WOS]	METABOLITES ; ANTIFUNGAL ; FUMIGATUS
收录类别	SCI
原文出处	10.3390/md11072682
语种	英语
WOS记录号	WOS:000328621500026
公开日期	2014-07-17
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/16528]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Wang, BG
作者单位	1.Chinese Acad Sci, Key Lab Expt Marine Biol, Inst Oceanol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	An, Chun-Yan,Li, Xiao-Ming,Li, Chun-Shun,et al. Aniquinazolines A-D, Four New Quinazolinone Alkaloids from Marine-Derived Endophytic Fungus Aspergillus nidulans[J]. MARINE DRUGS,2013,11(7):2682-2694.
APA	An, Chun-Yan.,Li, Xiao-Ming.,Li, Chun-Shun.,Wang, Ming-Hui.,Xu, Gang-Ming.,...&Wang, BG.(2013).Aniquinazolines A-D, Four New Quinazolinone Alkaloids from Marine-Derived Endophytic Fungus Aspergillus nidulans.MARINE DRUGS,11(7),2682-2694.
MLA	An, Chun-Yan,et al."Aniquinazolines A-D, Four New Quinazolinone Alkaloids from Marine-Derived Endophytic Fungus Aspergillus nidulans".MARINE DRUGS 11.7(2013):2682-2694.

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