Vibrational circular dichroism study for natural bioactive schizandrin and reassignment of its absolute configuration

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Vibrational circular dichroism study for natural bioactive schizandrin and reassignment of its absolute configuration
	He,Ping ; Wang,Xiangfen ; Guo,Xiujie ; Ji,Yannan ; Zhou,Chuanqi ; Shen,Shigang ; Hu,Dongbao ; Yang,Xiaolong ; Luo,Duqiang ; Dukor,Rina ; Zhu,Huajie
刊名	TETRAHEDRON LETTERS
	2014
卷号	55 期号:18 页码:2965-2968
关键词	Absolute configuration Schizandrin VCD ECD DIBENZOCYCLOOCTADIENE LIGNANS (+)-ISOSCHIZANDRIN
ISSN号	0040-4039
通讯作者	Zhu,HJ (reprint author),Hebei Univ,Coll Pharm Sci,Chinese Ctr Chiral,Key Lab Med Chem & Mol Diagnost,Educ Minist China,Baoding 071002,Peoples R China. ; hjzhu@mail.kib.ac.cn
英文摘要	Bioactive natural product (+)-schizandrin was assigned as (7S,8S) using NMR. Recently, we obtained (+)schizandrin from TCM Schisandra sphenanthera Rehd. et Wils. Its planar structure was well established using NMR and HR-MS including the reported references. Its absolute configuration is assigned using vibrational circular dichroism (VCD). By careful VCD investigation of (75,8S) and (75,8R) using B3LYP/6-311+G(d) methods, absolute configuration of (+)-schizandrin is assigned as (7S,8R). Electronic circular dichroism (ECD) was used for the discussion too and it gave the same conclusion. (C) 2014 Elsevier Ltd. All rights reserved.
学科主题	Chemistry
收录类别	SCI
资助信息	Hebei University; National Natural Science Foundation of China (NSFC) [21202033]; Natural Science Foundation of Hebei Province [C2012201047]; Foundation of Hebei University [179]
语种	英语
公开日期	2014-06-23
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/18111]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式 GB/T 7714	He,Ping,Wang,Xiangfen,Guo,Xiujie,et al. Vibrational circular dichroism study for natural bioactive schizandrin and reassignment of its absolute configuration[J]. TETRAHEDRON LETTERS,2014,55(18):2965-2968.
APA	He,Ping.,Wang,Xiangfen.,Guo,Xiujie.,Ji,Yannan.,Zhou,Chuanqi.,...&Zhu,Huajie.(2014).Vibrational circular dichroism study for natural bioactive schizandrin and reassignment of its absolute configuration.TETRAHEDRON LETTERS,55(18),2965-2968.
MLA	He,Ping,et al."Vibrational circular dichroism study for natural bioactive schizandrin and reassignment of its absolute configuration".TETRAHEDRON LETTERS 55.18(2014):2965-2968.