Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration

CORC > 上海应用物理研究所 > 中国科学院上海应用物理研究所 > 中科院上海应用物理研究所2011-2017年

	Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration
	Li, X. ; Niu, Y. ; Guo, H. ; Chen, H. ; Li, F. ; Zhang, J. ; Chen, W. ; Wu, Z. ; Deng, Y. ; Wei, J. ; Liu, C.
刊名	JOURNAL OF INSTRUMENTATION
	2013
卷号	8
ISSN号	1748-0221
英文摘要	The regenerative treatment of large osseous defects remains a formidable challenge in today. In the present study, we have synthesized biodegradable magnesium calcium phosphate biocement (MCPB) scaffolds with interconnected macroporous structure (100-600 mu m), as well as good bioactivity, biocompatibility and proper degradatibility. The results revealed that the porosity increased from 52% to 80% of MCPB scaffolds while the compressive strength decreased from 6.1MPa to 1.2MPa. We further assessed the effects of scaffolds on the rabbit femur cavity defect model in vivo by using synchrotron radiation X-ray microCT and microCT imaging, indicating that the MCPB scaffolds underwent gradually degradation and promoted the extensive neo-bone formation.
收录类别	SCI
语种	英语
WOS记录号	WOS:000322572900010
公开日期	2014-06-13
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/13861]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
推荐引用方式 GB/T 7714	Li, X.,Niu, Y.,Guo, H.,et al. Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration[J]. JOURNAL OF INSTRUMENTATION,2013,8.
APA	Li, X..,Niu, Y..,Guo, H..,Chen, H..,Li, F..,...&Liu, C..(2013).Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration.JOURNAL OF INSTRUMENTATION,8.
MLA	Li, X.,et al."Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration".JOURNAL OF INSTRUMENTATION 8(2013).