[5C+1N] Annulation of 2,4-pentadienenitriles with hydroxylamine: a synthetic route to multi-substituted 2-aminopyridines

	[5C+1N] Annulation of 2,4-pentadienenitriles with hydroxylamine: a synthetic route to multi-substituted 2-aminopyridines
	Xin XQ ; Huang P ; Xiang DX ; Zhang R ; Zhao FY ; Zhang N ; Dong DW
刊名	organic & biomolecular chemistry
	2013
卷号	11 期号:6 页码:1001-1006
关键词	SUBSTITUTED PYRIDINE-DERIVATIVES ONE-POT SYNTHESIS RECEPTOR ANTAGONISTS EFFICIENT METHOD DIRECT ACCESS MILD HETEROCYCLES INHIBITORS DISCOVERY CYCLOADDITION
ISSN号	1477-0520
通讯作者	zhang r
中文摘要	a facile and efficient synthetic route to multi-substituted 2-aminopyridines has been developed via a formal [5c + 1n] annulation of readily available 2,4-pentadienenitriles with hydroxylamine (nh2oh) under very mild conditions, which involves sequential intermolecular aza-nucleophilic addition of hydroxylamine, intramolecular aza-cyclization, and dehydration reactions.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000313664100016
公开日期	2014-04-18
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/50401]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Xin XQ,Huang P,Xiang DX,et al. [5C+1N] Annulation of 2,4-pentadienenitriles with hydroxylamine: a synthetic route to multi-substituted 2-aminopyridines[J]. organic & biomolecular chemistry,2013,11(6):1001-1006.
APA	Xin XQ.,Huang P.,Xiang DX.,Zhang R.,Zhao FY.,...&Dong DW.(2013).[5C+1N] Annulation of 2,4-pentadienenitriles with hydroxylamine: a synthetic route to multi-substituted 2-aminopyridines.organic & biomolecular chemistry,11(6),1001-1006.
MLA	Xin XQ,et al."[5C+1N] Annulation of 2,4-pentadienenitriles with hydroxylamine: a synthetic route to multi-substituted 2-aminopyridines".organic & biomolecular chemistry 11.6(2013):1001-1006.