High-efficiency localization of Na+-K+ ATPases on the cytoplasmic side by direct stochastic optical reconstruction microscopy

	High-efficiency localization of Na+-K+ ATPases on the cytoplasmic side by direct stochastic optical reconstruction microscopy
	Wu JZ ; Gao J ; Qi M ; Wang JZ ; Cai MJ ; Liu SH ; Hao X ; Jiang JG ; Wang HD
刊名	nanoscale
	2013
卷号	5 期号:23 页码:11582-11586
关键词	PROTEIN HETEROGENEITY ACTIN CYTOSKELETON FLUORESCENT-PROBES DIFFRACTION-LIMIT LIPID RAFTS RECEPTOR CYCLODEXTRINS NANOSCOPY CLUSTERS CELLS
ISSN号	2040-3364
通讯作者	jiang jg
中文摘要	we describe a concise and effective strategy towards precisely mapping na+-k+ atpases on the cytoplasmic side of cell membranes by direct stochastic optical reconstruction microscopy (dstorm). we found that most na+-k+ atpases are localized in different sizes of clusters on human red blood cell (hrbc) membranes, revealed by ripley's k-function analysis. further evidence that cholesterol depletion causes the dispersion of na+-k+ atpase clusters indicates that such clusters could be localized in cholesterol-enriched domains. our results suggest that na+-k+ atpases might aggregate within the lipid rafts to fulfill their functions.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000326982000026
公开日期	2014-04-16
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/50135]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Wu JZ,Gao J,Qi M,et al. High-efficiency localization of Na+-K+ ATPases on the cytoplasmic side by direct stochastic optical reconstruction microscopy[J]. nanoscale,2013,5(23):11582-11586.
APA	Wu JZ.,Gao J.,Qi M.,Wang JZ.,Cai MJ.,...&Wang HD.(2013).High-efficiency localization of Na+-K+ ATPases on the cytoplasmic side by direct stochastic optical reconstruction microscopy.nanoscale,5(23),11582-11586.
MLA	Wu JZ,et al."High-efficiency localization of Na+-K+ ATPases on the cytoplasmic side by direct stochastic optical reconstruction microscopy".nanoscale 5.23(2013):11582-11586.