Preparation and Biological Evaluation of Electrospun MSM/PLGA Dressing Containing Nano-silver

	Preparation and Biological Evaluation of Electrospun MSM/PLGA Dressing Containing Nano-silver
	Cui WW ; Liu Y ; Wang ZL ; Wang H ; Cui LG ; Zhang PB ; Chen XS
刊名	chemical journal of chinese universities-chinese
	2013
卷号	34 期号:3 页码:679-685
关键词	NANOPARTICLES NANOFIBERS BIOACTIVITY COMPOSITE GELATIN SKIN
ISSN号	0251-0790
通讯作者	liu y
中文摘要	antibacterial dressings containing nano-silver powders (n-ag)/dimethyl sulfoxide (msm)/poly(lactide-co-glycolide) (plga) were prepared by electrospinning. field emission scanning electron microscope( esem) and energy-dispersive x-ray spectroscopy(edx) were applied for the investigation of the microscopic structure and surface elements of the dressings as well as mechanical properties, water absorption, cell compatibility and antibacterial function so that we could comprehensively evaluate the functionality and practicability of dressings. the results show that the fibers of dressing is a crossing grid-like structure, interconnected, and gradually enhenced the mechanical strength of fibers with increasing of n-ag content, as well as water absorption ability. when the n-ag content is more than 1% (mass fraction), the dressings show a good antibacterial ability against the gram-positive staphylococci and gram-negative escherichia coli. cell experimental results show that when the content of n-ag is between 0. 01%-10%, the dressings are non-toxic or low toxicity; when the content of n-ag is less than 1%, it contributes to the growth and proliferation of cells. therefore, we conclude that the dressing has a good biocompatibility and antibacterial properties, and has broad application prospects in a functional medical dressings research and industrial area.
收录类别	SCI收录期刊论文
WOS记录号	WOS:000317085500033
公开日期	2014-04-16
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/49985]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Cui WW,Liu Y,Wang ZL,et al. Preparation and Biological Evaluation of Electrospun MSM/PLGA Dressing Containing Nano-silver[J]. chemical journal of chinese universities-chinese,2013,34(3):679-685.
APA	Cui WW.,Liu Y.,Wang ZL.,Wang H.,Cui LG.,...&Chen XS.(2013).Preparation and Biological Evaluation of Electrospun MSM/PLGA Dressing Containing Nano-silver.chemical journal of chinese universities-chinese,34(3),679-685.
MLA	Cui WW,et al."Preparation and Biological Evaluation of Electrospun MSM/PLGA Dressing Containing Nano-silver".chemical journal of chinese universities-chinese 34.3(2013):679-685.