Chemical Constituent Changes of Wu-tou-tang in Compatibility Process with Fritillariae cirrhosae and Fritillariae thunbergii

	Chemical Constituent Changes of Wu-tou-tang in Compatibility Process with Fritillariae cirrhosae and Fritillariae thunbergii
	Qi Y ; Li SZ ; Zhu HB ; Song FR ; Lin N ; Liu ZQ
刊名	chemical journal of chinese universities-chinese
	2013
卷号	34 期号:6 页码:1374-1378
关键词	NONTOXIC ACONITINE-HYDROLYSATE BURN-ASSOCIATED INFECTIONS SIMPLEX-VIRUS TYPE-1 MASS-SPECTROMETRY CANDIDA-ALBICANS RADIX-ACONITI ALKALOIDS COMBINATION BENZOYLMESACONINE FORMULA
ISSN号	0251-0790
通讯作者	liu zq
中文摘要	wu-tou-tang was chosen to investigate the chemical constituent changes of aconitum-fritillariae combination taboo in prescription. the ultra performance liquid chromatography coupled with mass spectrometry(uplc-ms) and tandem mass spectrometry methods were used to evaluate the chemical composition of wu-tou-tang and its co-decoction with fritillariae cirrhosae and fritillariae thunbergiiin with a mass ratio of 1 : 1. the total ion chromatograms(tic) of the co-decoctions were processed by mzmine 2, and then the dataset was analyzed by partial least squares discriminant analysis(pls-da). significant differences between the group of wu-tou-tang and wu-tou-tang combined with fritillariae cirrhosae and fritillariae thunbergii in pls-da model were observed. seven of the eight potential chemical markers in wu-tou-tang and fritillariae cirrhosae compatibility process were identified, the relative content of neoline, fuziline and benzoylmesaconine increased and talatizidine, 10-oh benzoylmesaconine, 10-oh benzoylaconine and benzoyldeoxyaconine decreased. chuanfumine, songorine, talatizidine, neoline, fuziline, benzoylmesaconine and 10-0h benzoylmesaconine were found as potential chemical markers in wu-tou-tang and fritillariae thunbergii compatibility process, respectively. the result shows that relative content of all potential chemical markers in wu-tou-tang and fritillariae thunbergii co-decoction was less than that in wu-tou-tang.
收录类别	SCI收录期刊论文
语种	中文
WOS记录号	WOS:000321080000011
公开日期	2014-04-15
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/49796]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Qi Y,Li SZ,Zhu HB,et al. Chemical Constituent Changes of Wu-tou-tang in Compatibility Process with Fritillariae cirrhosae and Fritillariae thunbergii[J]. chemical journal of chinese universities-chinese,2013,34(6):1374-1378.
APA	Qi Y,Li SZ,Zhu HB,Song FR,Lin N,&Liu ZQ.(2013).Chemical Constituent Changes of Wu-tou-tang in Compatibility Process with Fritillariae cirrhosae and Fritillariae thunbergii.chemical journal of chinese universities-chinese,34(6),1374-1378.
MLA	Qi Y,et al."Chemical Constituent Changes of Wu-tou-tang in Compatibility Process with Fritillariae cirrhosae and Fritillariae thunbergii".chemical journal of chinese universities-chinese 34.6(2013):1374-1378.