A label-free and signal-on supersandwich fluorescent platform for Hg2+ sensing
Yuan T ; Hu LZ ; Liu ZY ; Qi WJ ; Zhu SY ; Aziz-ur-Rehman ; Xu GB
刊名analytica chimica acta
2013
卷号793页码:86-89
关键词SELECTIVE DETECTION COMPLEX MATRICES AQUEOUS-SOLUTION DNA NANOPARTICLES MERCURY(II) AU BEACON PROBE IONS
ISSN号0003-2670
通讯作者xu gb
中文摘要a label-free supersandwich fluorescent assay was demonstrated for the first time by taking hg2+ as a detection candidate. the principle of the proposed supersandwich fluorescent platform is based on the formation of supersandwich structure by t-hg2+-t coordination and the fluorescence enhancement of the intercalated genefinder (gf) in double strand dna (dsdna). such supersandwich fluorescent dna sensor exhibits a linear range of 10-300 nm for the detection of hg2+, with a detection limit of 2.5 nm on the basis of the 3 sigma/slope (sigma represents the standard deviation of the blank samples), which is well below the permit of the u.s. environmental protection agency (<10 nm). the detection can be fulfilled in less than 10 min. the proposed mix-and-detect fluorescent platform exhibits excellent sensitivity, selectivity, and convenient manipulation. the assay was successfully used to detect hg2+ in the lake water samples, which suggested its potential in practical samples. (c) 2013 elsevier b.v. all rights reserved.
收录类别SCI收录期刊论文
语种英语
WOS记录号WOS:000323855400011
公开日期2014-04-15
内容类型期刊论文
源URL[http://ir.ciac.jl.cn/handle/322003/49630]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
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Yuan T,Hu LZ,Liu ZY,et al. A label-free and signal-on supersandwich fluorescent platform for Hg2+ sensing[J]. analytica chimica acta,2013,793:86-89.
APA Yuan T.,Hu LZ.,Liu ZY.,Qi WJ.,Zhu SY.,...&Xu GB.(2013).A label-free and signal-on supersandwich fluorescent platform for Hg2+ sensing.analytica chimica acta,793,86-89.
MLA Yuan T,et al."A label-free and signal-on supersandwich fluorescent platform for Hg2+ sensing".analytica chimica acta 793(2013):86-89.
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