Recent progress in G-quadruplex DNA in deep eutectic solvent

	Recent progress in G-quadruplex DNA in deep eutectic solvent
	Zhao CQ ; Qu XG
刊名	methods
	2013
卷号	64 期号:1 页码:52-58
关键词	TELOMERIC G-QUADRUPLEX INTRAMOLECULAR G-QUADRUPLEX HYDRATED IONIC LIQUIDS K+ SOLUTION HIV-1 INTEGRASE NUCLEIC-ACIDS SEQUENCE STABILITY FORMS BINDING
ISSN号	1046-2023
通讯作者	qu xg
中文摘要	guanine-rich nucleic acids are known to form four-stranded g-quadruplex structures which are attracting increasing attention in diverse areas such as biology, medicinal chemistry, supramolecular chemistry and nanotechnology. to date, the handling media for dna has largely been limited to an aqueous phase. since many chemical reactions and devices are required to be performed under strictly anhydrous conditions, even at high temperature, it is meaningful but challenging to conduct g-quadruplex dna in water-free medium. recently, deep eutectic solvent (des), a related material to ionic liquilds (ils) was considered as a new class of anhydrous media for dna. this review highlights the stability, structure, folding dynamics and thermodynamics of g-quadruplex in des. spectroscopic methodologies, like circular dichroism, uv and fluorescence, are mainly employed in these studies. (c) 2013 elsevier inc. all rights reserved.
收录类别	SCI收录期刊论文
语种	英语
WOS记录号	WOS:000326430100008
公开日期	2014-04-15
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/49506]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Zhao CQ,Qu XG. Recent progress in G-quadruplex DNA in deep eutectic solvent[J]. methods,2013,64(1):52-58.
APA	Zhao CQ,&Qu XG.(2013).Recent progress in G-quadruplex DNA in deep eutectic solvent.methods,64(1),52-58.
MLA	Zhao CQ,et al."Recent progress in G-quadruplex DNA in deep eutectic solvent".methods 64.1(2013):52-58.