Inactivation of He la cancer cells by an atmospheric pressure cold plasma jet

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	Inactivation of He la cancer cells by an atmospheric pressure cold plasma jet
	Huang, J ; Chen, W ; Li, H ; Wang, PY ; Yang, SZ
刊名	ACTA PHYSICA SINICA
	2013
卷号	62 期号:6
关键词	atmospheric pressure cold plasma jet Hela cancer cells survival rate optical emission spectra
ISSN号	1000-3290
通讯作者	Huang, J (reprint author), Chinese Acad Sci, Inst Phys, Beijing Natl Lab Condensed Matter Phys, Key Lab Soft Matter Phys, Beijing 100190, Peoples R China.
中文摘要	An inactivation mechanism study on Hela cancer cells by means of an atmospheric pressure cold plasma jet is presented. Cell morphology is observed under an inverted microscope after plasma treatment. The neutral red uptake assay provides quantitative evaluations of cell viability under different conditions. The effect of the inactivation efficiency of Hela cancer cells in the argon (900 mL/min) with addition of different amount of oxygen (1%, 2%, 4%, 8%) into atmospheric pressure cold plasma jet is discussed under the fixed power 18 W. Results show that 2% O-2 addition provides the best inactivation efficiency, and the survival rate can be reduced to 7% after 180 s treatment. When the oxygen addition exceeds 2%, the inactivation efficiency gradually weakens. The effect is not so good as that in pure argon plasma when the oxygen addition arrives at 8%. According to the emission spectrum of the plasmum, it is concluded that the reactive oxygen species in the plasma play a key role in cancer cell inactivation process.
资助信息	National Natural Science Foundation of China [11275261, 11005151]
语种	中文
公开日期	2014-01-16
内容类型	期刊论文
源URL	[http://ir.iphy.ac.cn/handle/311004/57106]
专题	物理研究所_物理所公开发表论文_物理所公开发表论文_期刊论文
推荐引用方式 GB/T 7714	Huang, J,Chen, W,Li, H,et al. Inactivation of He la cancer cells by an atmospheric pressure cold plasma jet[J]. ACTA PHYSICA SINICA,2013,62(6).
APA	Huang, J,Chen, W,Li, H,Wang, PY,&Yang, SZ.(2013).Inactivation of He la cancer cells by an atmospheric pressure cold plasma jet.ACTA PHYSICA SINICA,62(6).
MLA	Huang, J,et al."Inactivation of He la cancer cells by an atmospheric pressure cold plasma jet".ACTA PHYSICA SINICA 62.6(2013).