New steroids and sesquiterpene from Turraea pubescens | |
Yuan, Chun-Mao1,2; Tang, Gui-Hua2; Wang, Xiao-Ying2; Zhang, Yu2; Cao, Ming-Ming2; Li, Xiao-Hui2; Li, Yan2; Li, Shun-Lin2; Di, Ying-Tong2; He, Hong-Ping2 | |
刊名 | FITOTERAPIA |
2013-10-01 | |
卷号 | 90页码:119-125 |
关键词 | Turraea pubescens Meliaceae Steroids Sesquiterpene Anti-inflammatory |
ISSN号 | 0367-326X |
通讯作者 | He,HP (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.,hehongping@mail.kib.ac.cn ; haoxj@mail.kib.ac.cn ; huimhua@163.com |
英文摘要 | Four new compounds, including three new steroids (1-3) and one new sesquiterpene (6), and two new natural products (4-5), as well as three known steroids (7-9) were isolated from the twigs of Turraea pubescens. Compounds 3-5 are C-22 steroids isolated from the Meliaceae family for the first time. Their structures were elucidated by extensive NMR and MS analyses. Compound 1 exhibited inhibitory activity against lipopolysaccharide (LPS) induced nitric oxide (NO) production in RAW264.7 cells with an IC50 value of 11.5 mu M. (C) 2013 Elsevier B.V. All rights reserved. |
学科主题 | Pharmacology & Pharmacy |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
研究领域[WOS] | Pharmacology & Pharmacy |
关键词[WOS] | LIMONOIDS ; FLORIBUNDA ; SKELETON |
收录类别 | SCI |
资助信息 | National Basic Research Program of China (973 Program) [2009CB522300, 2009CB940900];National Natural Science Funding of China [31170332];Young Academic and Technical Leader Raising Foundation of Yunnan Province [2010CI047] |
语种 | 英语 |
WOS记录号 | WOS:000326427600016 |
公开日期 | 2014-01-13 |
内容类型 | 期刊论文 |
源URL | [http://ir.kib.ac.cn/handle/151853/17416] |
专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
作者单位 | 1.Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China |
推荐引用方式 GB/T 7714 | Yuan, Chun-Mao,Tang, Gui-Hua,Wang, Xiao-Ying,et al. New steroids and sesquiterpene from Turraea pubescens[J]. FITOTERAPIA,2013,90:119-125. |
APA | Yuan, Chun-Mao.,Tang, Gui-Hua.,Wang, Xiao-Ying.,Zhang, Yu.,Cao, Ming-Ming.,...&Hua, Hui-Ming.(2013).New steroids and sesquiterpene from Turraea pubescens.FITOTERAPIA,90,119-125. |
MLA | Yuan, Chun-Mao,et al."New steroids and sesquiterpene from Turraea pubescens".FITOTERAPIA 90(2013):119-125. |
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