Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates | |
Xu, Wenjie3; Zhu, Chenglong3; Gao, Xueli3; Wu, Baosheng3; Xu, Han2; Hu, Mingliang3; Zeng, Honghui1; Gan, Xiaoni1; Feng, Chenguang3; Zheng, Jiangmin3 | |
刊名 | ELIFE |
2023-12-22 | |
卷号 | 12页码:51 |
关键词 | Pseudoliparis swirei muscle brain Liparis tanakae Other |
ISSN号 | 2050-084X |
DOI | 10.7554/eLife.87198 |
英文摘要 | As the deepest vertebrate in the ocean, the hadal snailfish (Pseudoliparis swirei), which lives at a depth of 6,000-8,000 m, is a representative case for studying adaptation to extreme environments. Despite some preliminary studies on this species in recent years, including their loss of pigmentation, visual and skeletal calcification genes, and the role of trimethylamine N-oxide in adaptation to high-hydrostatic pressure, it is still unknown how they evolved and why they are among the few vertebrate species that have successfully adapted to the deep-sea environment. Using genomic data from different trenches, we found that the hadal snailfish may have entered and fully adapted to such extreme environments only in the last few million years. Meanwhile, phylogenetic relationships show that they spread into different trenches in the Pacific Ocean within a million years. Comparative genomic analysis has also revealed that the genes associated with perception, circadian rhythms, and metabolism have been extensively modified in the hadal snailfish to adapt to its unique environment. More importantly, the tandem duplication of a gene encoding ferritin significantly increased their tolerance to reactive oxygen species, which may be one of the important factors in their adaptation to high-hydrostatic pressure. |
资助项目 | National Key Research and Development Program of China ; National Natural Science Foundation of China ; The 1000 Talent Project Shaanxi Province ; Fundamental Research Funds of Northwestern Polytechnic University ; Strategic Priority Research Program of Chinese Academy of Sciences |
WOS关键词 | HIGH HYDROSTATIC-PRESSURE ; PHYLOGENETIC ANALYSIS ; NA+/K+-ATPASE ; PROTEIN ; ZEBRAFISH ; ALIGNMENT ; INSIGHTS ; SYSTEM ; MEMBRANE ; FLUIDITY |
WOS研究方向 | Life Sciences & Biomedicine - Other Topics |
语种 | 英语 |
出版者 | eLIFE SCIENCES PUBL LTD |
WOS记录号 | WOS:001129824200001 |
资助机构 | National Key Research and Development Program of China ; National Natural Science Foundation of China ; The 1000 Talent Project Shaanxi Province ; Fundamental Research Funds of Northwestern Polytechnic University ; Strategic Priority Research Program of Chinese Academy of Sciences |
内容类型 | 期刊论文 |
源URL | [http://ir.idsse.ac.cn/handle/183446/10854] |
专题 | 深海科学研究部_深海生物学研究室_深海生物蛋白质组学及分子生物学研究组 |
通讯作者 | He, Shunping; Wang, Kun |
作者单位 | 1.Chinese Acad Sci, Key Lab Aquat Biodivers & Conservat, Inst Hydrobiol, Wuhan, Peoples R China 2.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya, Peoples R China 3.Northwestern Polytech Univ, Sch Ecol & Environm, Xian, Peoples R China |
推荐引用方式 GB/T 7714 | Xu, Wenjie,Zhu, Chenglong,Gao, Xueli,et al. Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates[J]. ELIFE,2023,12:51. |
APA | Xu, Wenjie.,Zhu, Chenglong.,Gao, Xueli.,Wu, Baosheng.,Xu, Han.,...&Wang, Kun.(2023).Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates.ELIFE,12,51. |
MLA | Xu, Wenjie,et al."Chromosome-level genome assembly of hadal snailfish reveals mechanisms of deep-sea adaptation in vertebrates".ELIFE 12(2023):51. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论