Atmospheric seeing is one of the most important parameters for evaluating and monitoring an astronomical site.Moreover,being able to predict the seeing in advance can guide observing decisions and significantly improve the efficiency of telescopes.However,it is not always easy to obtain long term and continuous seeing measurements from a standard instrument such as differential image motion monitor(DIMM),especially for those unattended observatories with challenging environments such as Dome A,Antarctica.In this paper,we present a novel machine learning-based framework for estimating and predicting seeing at a height of 8 m at Dome A,Antarctica,using only the data from a multi-layer automated weather station(AWS).In comparison with DIMM data,our estimate has a root mean square error(RMSE)of 0.18 arcsec,and the RMSE of predictions 20 min in the future is 0.12 arcsec for the seeing range from 0 to 2.2 arcsec.Compared with the persistence,where the forecast is the same as the last data point,our framework reduces the RMSE by 37 per cent.Our method predicts the seeing within a second of computing time,making it suitable for real-time telescope scheduling.