Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns

doi:10.1186/s12864-023-09790-8

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室

	Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns
	Xu, Tongli 1,2; Cui, Yulin 3; Qin, Song 1,5; Wang, Yin-Chu 1,4,5
刊名	BMC GENOMICS
	2023-11-16
卷号	24 期号:1 页码:8
关键词	Lectin Gene family Evolution Cyanobacteria Motif
ISSN号	1471-2164
DOI	10.1186/s12864-023-09790-8
通讯作者	Qin, Song(sqin@yic.ac.cn) ; Wang, Yin-Chu(ycwang@yic.ac.cn)
英文摘要	Lectins are glycoproteins that can bind to specific carbohydrates, and different lectin families exhibit different biological activities. They are also present in the cyanobacteria and many of them have shown excellent therapeutic effect, which deserve for bioprospecting. However, in comparison to those from terrestrial plants, the current knowledge on cyanobacterial lectins is very limited. To this end, genome-wide analyses were performed to find out their evolutionary mode and motif patterns in 316 genomes of representative taxa. In results, 196 putative cyanobacterial lectins were dig out and 105 of them were classified into known families. Seven lectins were found to be belonged to distinct two lectin families, and they may have the potential activities of both lectin families. Whereas no MFP-2, Chitin, and Nictaba family lectins were found. What's more, the Legume lectin-like lectin family was found to be the richest and most complex in cyanobacteria, which could be a main research direction for future cyanobacterial lectin bioprospecting and development. Our classification and prediction of cyanobacteria lectins is expected to provide assistance in the development of lectin-based medicine and provide solutions to the current thorny viral and tumor diseases in humans.
WOS关键词	ALGA EUCHEUMA-SERRA ; BINDING
WOS研究方向	Biotechnology & Applied Microbiology ; Genetics & Heredity
语种	英语
WOS记录号	WOS:001103440800002
资助机构	Not applicable.
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/33204]
专题	海岸带生物学与生物资源利用重点实验室
通讯作者	Qin, Song; Wang, Yin-Chu
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Shandong Univ Tradit Chinese Med, Jinan 250335, Peoples R China 3.Binzhou Med Univ, Yantai 264003, Peoples R China 4.Natl Basic Sci Data Ctr, Beijing 100190, Peoples R China 5.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China
推荐引用方式 GB/T 7714	Xu, Tongli,Cui, Yulin,Qin, Song,et al. Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns[J]. BMC GENOMICS,2023,24(1):8.
APA	Xu, Tongli,Cui, Yulin,Qin, Song,&Wang, Yin-Chu.(2023).Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns.BMC GENOMICS,24(1),8.
MLA	Xu, Tongli,et al."Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns".BMC GENOMICS 24.1(2023):8.