Water-soluble amino functionalized chitosan: Preparation, characterization, antioxidant and antibacterial activities

doi:10.1016/j.ijbiomac.2022.07.187

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 海岸带生物学与生物资源利用重点实验室

	Water-soluble amino functionalized chitosan: Preparation, characterization, antioxidant and antibacterial activities
	Yuan, Yuting 2,3; Tan, Wenqiang 1,3; Zhang, Jingjing 1,3; Li, Qing 1,3; Guo, Zhanyong 1,2,3
刊名	INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
	2022-09-30
卷号	217 页码:969-978
关键词	Amino functionalized chitosan derivative Antibacterial activity Antioxidant activity Water -solubility
ISSN号	0141-8130
DOI	10.1016/j.ijbiomac.2022.07.187
通讯作者	Tan, Wenqiang(wqtan@yic.ac.cn) ; Guo, Zhanyong(zhanyongguo@hotmail.com)
英文摘要	Amino functionalized chitosan has attracted much attention because of the fascinated bioactivities. In our study, a novel water-soluble amino functionalized chitosan bearing free amino group at C-2 and quaternary ammonium moiety contained free amino group at C-6 (5c) was prepared by a four-step method. The structural characterization was identified by FTIR and 1H NMR spectroscopy. The water-solubility and antioxidant activities against hydroxyl, DPPH radicals and reducing power were estimated. The results displayed that amino functionalized chitosan 5c exhibited improved water-solubility and antioxidant ability, especially its DPPH scavenging rate reached about 90 % at the minimum test concentration of 0.10 mg/mL. Besides, antibacterial tests showed that amino functional chitosan 5c had best antibacterial activities, which indicated that amino group made main contribution to the enhanced bioactivities. In short, the novel chitosan 5c possessed enhanced water-solubility and excellent antioxidant and antibacterial activities, which could provide novel strategy for the development of antioxidant and antibacterial agents in biomedicine and food fields.
WOS关键词	N-PHTHALOYL-CHITOSAN ; QUATERNARY AMMONIUM ; DERIVATIVES ; MEMBRANE ; DESIGN ; 6-AMINO-6-DEOXYCHITOSAN
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
语种	英语
WOS记录号	WOS:000878627200010
资助机构	Youth Innovation Promotion Association CAS ; National Key Research and Develop- ment Program of China
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/32002]
专题	海岸带生物学与生物资源利用重点实验室
通讯作者	Tan, Wenqiang; Guo, Zhanyong
作者单位	1.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China
推荐引用方式 GB/T 7714	Yuan, Yuting,Tan, Wenqiang,Zhang, Jingjing,et al. Water-soluble amino functionalized chitosan: Preparation, characterization, antioxidant and antibacterial activities[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2022,217:969-978.
APA	Yuan, Yuting,Tan, Wenqiang,Zhang, Jingjing,Li, Qing,&Guo, Zhanyong.(2022).Water-soluble amino functionalized chitosan: Preparation, characterization, antioxidant and antibacterial activities.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,217,969-978.
MLA	Yuan, Yuting,et al."Water-soluble amino functionalized chitosan: Preparation, characterization, antioxidant and antibacterial activities".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 217(2022):969-978.