The directional polarimetric camera (DPC), developed by Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Science, is a satellite sensor used to observe the polarization and directionality of the earth’s reflectance. It acquires the two-dimensional image of the earth with a large field of view (118.74°) and a high spatial resolution (3.3 km) in 8 spectral bands. The first DPC was successfully launched onboard the GaoFen-5 satellite in May 2018, subject to the Chinese high-resolution earth observation program. In this paper, a set of systematic and complete pre-flight calibrations of the DPC are proposed to ensure the effective characterization for in-flight calibration, so as to ensure the accuracy of DPC measured radiation polarization data and the reliability of inversion results. Since the geometric calibration method of the DPC has been presented in an early companion paper [Appl. Opt. 59 226 (2020)], this paper will not introduce it in detail. Instead, the geometric calibration results of each spectral band together with a discussion on the origin of differences between spectral bands are analyzed, and the error analysis of the method is conducted. The results of the DPC geometric calibration is that the residuals of all spectral bands are less than 0.1 pixel. For radiometric calibration, the radiometric models of non-polarized bands and polarized bands are derived in detail, respectively, and the specific calibration methods with error analysis, equipment, and main results with their related accuracies for each parameter of the radiometric models are described. To verify the accuracy of calibration parameters, a series of polarization detection accuracy verification experiments based on a non-polarized radiation source, a polarizing system, and a natural scene were carried out. The experimental results show that the maximum deviation of degree of polarization between the set values of the polarizing system and measured values of the DPC at the corresponding positions of four field of view angles of 0, 15, 30, and 45 degrees of each polarized spectral band is 0.009, 0.004, and 0.003, respectively. The average error in measuring the degree of polarization of a non-polarized light source by all pixels in the three polarized bands is 0.0043, 0.0046, and 0.0037, respectively. And the relative deviations of each field of view are within 0.020 when the DPC and CE318N simultaneously measure the DoLP of sky. All of these prove the effectiveness of the pre-flight calibration.