Construction of Ag nanowire@Au nanoparticle nano nests with densely stacked small gaps for actively trapping molecules to realize diversity SERS detection

doi:10.1039/d2an00527a

	Construction of Ag nanowire@Au nanoparticle nano nests with densely stacked small gaps for actively trapping molecules to realize diversity SERS detection
	Xie, Tao 1,3; Li, Pan 1,2; Ge, Meihong 1,3; Chen, Siyu 1,3; Huang, Guangyao 1,3; Li, Junxiang 1,3; Gong, Meiting 1,3; Weng, Shirui 1,2; Yang, Liangbao 1,2
刊名	ANALYST
	2022-04-28
ISSN号	0003-2654
DOI	10.1039/d2an00527a
通讯作者	Li, Pan(lipan2011@iim.ac.cn) ; Yang, Liangbao(lbyang@iim.ac.cn)
英文摘要	Highly sensitive surface-enhanced Raman spectroscopy (SERS) sensing not only depends on an active substrate with high density of hot spots, but also depends more on whether the molecules can effectively enter the hot spot region. In this paper, a new SERS detection method based on the nano nest model is developed to autonomously capture molecules into hot spots. The nano nest is composed of silver nanowires modified with gold nanoparticles (Ag NW@Au NPs), which not only form high density hot spots between particles or particles-wires, but also have a coupled electromagnetic field enhancement effect. The SERS detection method based nano nest actively traps molecules through the capillary stage, and makes the molecules move toward densely stacked small gaps (hot spots) by capillary action. The above method has been used to detect different kinds of molecules, such as pesticide residues, adenosine triphosphate in culture medium, and antibiotic residues in aquatic products. In addition, an in situ SERS monitoring of allergic reactions was also performed using nano nests with the feature of actively trapping molecules into the hot spots. This nano nest will be able to perform a direct monitoring of biochemical reactions, and more importantly, it can provide a new scheme for SERS detection.
资助项目	Research Instrument and Equipment Development Project, Chinese Academy of Sciences[YJKYYQ20200022] ; Anhui Provincial Key RD Program[202104d07020002] ; National Science Foundation of China[21974142]
WOS关键词	ENHANCED RAMAN-SCATTERING ; MOSQUITO BITES ; NEEDLE ; SENSOR
WOS研究方向	Chemistry
语种	英语
出版者	ROYAL SOC CHEMISTRY
WOS记录号	WOS:000793737000001
资助机构	Research Instrument and Equipment Development Project, Chinese Academy of Sciences ; Anhui Provincial Key RD Program ; National Science Foundation of China
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/130829]
专题	中国科学院合肥物质科学研究院
通讯作者	Li, Pan; Yang, Liangbao
作者单位	1.Chinese Acad Sci, Hefei Inst Phys Sci, Inst Hlth & Med Technol, Hefei 230031, Peoples R China 2.Chinese Acad Sci, Hefei Canc Hosp, Dept Pharm, Hefei 230031, Anhui, Peoples R China 3.Univ Sci & Technol China, Hefei 230026, Anhui, Peoples R China
推荐引用方式 GB/T 7714	Xie, Tao,Li, Pan,Ge, Meihong,et al. Construction of Ag nanowire@Au nanoparticle nano nests with densely stacked small gaps for actively trapping molecules to realize diversity SERS detection[J]. ANALYST,2022.
APA	Xie, Tao.,Li, Pan.,Ge, Meihong.,Chen, Siyu.,Huang, Guangyao.,...&Yang, Liangbao.(2022).Construction of Ag nanowire@Au nanoparticle nano nests with densely stacked small gaps for actively trapping molecules to realize diversity SERS detection.ANALYST.
MLA	Xie, Tao,et al."Construction of Ag nanowire@Au nanoparticle nano nests with densely stacked small gaps for actively trapping molecules to realize diversity SERS detection".ANALYST (2022).