The Role of Jinhuang Powder to Prevent Adverse Effects of Subcutaneous Injection of Enoxaparin Sodium

doi:10.1155/2022/7806659

	The Role of Jinhuang Powder to Prevent Adverse Effects of Subcutaneous Injection of Enoxaparin Sodium
	Zhang, Meng 1,2; Zhang, Xiang 1,2; Wang, Chunlan 1,2; Shen, Yangfang 1,2; Fu, Jianan 1,2
刊名	EMERGENCY MEDICINE INTERNATIONAL
	2022-08-24
卷号	2022
ISSN号	2090-2840
DOI	10.1155/2022/7806659
通讯作者	Wang, Chunlan(wangcl@zjcc.org.cn) ; Shen, Yangfang(shenyangfang2022@163.com)
英文摘要	Objective. To determine the role of Jinhuang Powder to prevent adverse effects of subcutaneous injection of enoxaparin sodium. Methods. The clinical data of 97 patients with cervical cancer who were treated with subcutaneous injection of enoxaparin through the lower margin of the deltoid muscle of the upper arm in Zhejiang Tumor Hospital from August 2020 to August 2021 were retrospectively analyzed. All patients were divided into the control group (n = 39) and the research group (n = 58) according to the different use time periods of Jinhuang Powder. The research group was treated with Jinhuang Powder and enoxaparin sodium at the same time. The control group started to use Jinhuang Powder after the adverse reactions occurred. The induration, subcutaneous bleeding events, and pain were statistically analyzed. Results. The incidence of induration (3.4% vs 15.4%, P=0.036) and subcutaneous hemorrhage (37.9% vs 76.9%, P=0.003) in the research group was significantly lower than that in the control group. The pain in the research group was lighter than that in the control group (grade 0-4 pain: 70% vs 28.2%, 19% vs 30.8%, 8.6% vs 23.1%, 1.7% vs 12.8%, 1.7% vs 5.1%, P=0.001). Conclusion. Preventive use of Jinhuang Powder can significantly reduce the incidence of subcutaneous induration and subcutaneous bleeding and can effectively alleviate the local pain of injection. It is worthy of further study to clarify its role and mechanism.
资助项目	Zhejiang Medical and Health Science and Technology Plan Project ; [2019KY036]
WOS研究方向	Emergency Medicine
语种	英语
出版者	HINDAWI LTD
WOS记录号	WOS:000873995100001
资助机构	Zhejiang Medical and Health Science and Technology Plan Project
内容类型	期刊论文
源URL	[http://ir.hfcas.ac.cn:8080/handle/334002/129885]
专题	中国科学院合肥物质科学研究院
通讯作者	Wang, Chunlan; Shen, Yangfang
作者单位	1.Chinese Acad Sci, Inst Basic Med & Canc IBMC, Hangzhou, Peoples R China 2.Univ Chinese Acad Sci, Zhejiang Canc Hosp, Dept Gynecol Radiat Oncol, Canc Hosp, Hangzhou, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Meng,Zhang, Xiang,Wang, Chunlan,et al. The Role of Jinhuang Powder to Prevent Adverse Effects of Subcutaneous Injection of Enoxaparin Sodium[J]. EMERGENCY MEDICINE INTERNATIONAL,2022,2022.
APA	Zhang, Meng,Zhang, Xiang,Wang, Chunlan,Shen, Yangfang,&Fu, Jianan.(2022).The Role of Jinhuang Powder to Prevent Adverse Effects of Subcutaneous Injection of Enoxaparin Sodium.EMERGENCY MEDICINE INTERNATIONAL,2022.
MLA	Zhang, Meng,et al."The Role of Jinhuang Powder to Prevent Adverse Effects of Subcutaneous Injection of Enoxaparin Sodium".EMERGENCY MEDICINE INTERNATIONAL 2022(2022).