Gentiana straminea Maxim. polysaccharide decolored via high-throughput graphene-based column and its anti-inflammatory activity | |
Shi, S; Wang, GC; Liu, J; Liu, SA; Xu, QY; Lan, X; Feng, JX; Sun, J; Zhang, WT; Wang, JL | |
刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES |
2021 | |
卷号 | 193页码:1727 |
英文摘要 | Gentiana straminea Maxim. exhibits various biological activities. However, the purification and functions of polysaccharides in Gentiana straminea Maxim. have never been reported. Herein, by proposing a flexible 3D graphene-based decoloration column (3DD column), Gentiana straminea Maxim. polysaccharide (GMP) was high-throughput obtained and its anti-inflammatory activity was investigated. Benefiting from the large macroporous network of 3D NH2 -graphene oxide hydrogel with selective adsorption towards pigments, the 3DD column exhibits high decoloration ratio (96.41%). In addition, the 3DD column provides superior practical functionality as compared to the traditional approaches, which are time-consuming and need toxic solvents, and exhibiting widespread-application for the purification of polysaccharide from other common plant species. More importantly, the decolored GMP as a natural product has promising anti-inflammatory activity on RAW264.7 cells without negative impact on cell viability. Overall, this work reveals a new functional polysaccharides and provides a flexible approach for polysaccharide decoloration, exhibiting a promising prospect for natural polysaccharides in practical application of pharmaceutical. |
内容类型 | 期刊论文 |
源URL | [http://210.75.249.4/handle/363003/61329] |
专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Shi, S,Wang, GC,Liu, J,et al. Gentiana straminea Maxim. polysaccharide decolored via high-throughput graphene-based column and its anti-inflammatory activity[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2021,193:1727. |
APA | Shi, S.,Wang, GC.,Liu, J.,Liu, SA.,Xu, QY.,...&Wang, JL.(2021).Gentiana straminea Maxim. polysaccharide decolored via high-throughput graphene-based column and its anti-inflammatory activity.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,193,1727. |
MLA | Shi, S,et al."Gentiana straminea Maxim. polysaccharide decolored via high-throughput graphene-based column and its anti-inflammatory activity".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 193(2021):1727. |
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