Structural Integrity in the Genu of Corpus Callosum Predicts Conflict-induced Functional Connectivity Between Medial Frontal Cortex and Right Posterior Parietal Cortex

doi:10.1016/j.neuroscience.2017.10.017

CORC > 兰州理工大学 > 兰州理工大学 > 土木工程学院

	Structural Integrity in the Genu of Corpus Callosum Predicts Conflict-induced Functional Connectivity Between Medial Frontal Cortex and Right Posterior Parietal Cortex
	Liu, Peng 1,2; Yu, Yang 1; Gao, Shudan 1; Sun, Jinbo 1; Yang, Xuejuan 1; Liu, Peng a 1; Qin, Wei 1
刊名	NEUROSCIENCE
	2017-12-16
卷号	366 页码:162-171
关键词	functional connectivity structural connectivity individual difference phase synchronization
ISSN号	0306-4522
DOI	10.1016/j.neuroscience.2017.10.017
英文摘要	Studies using the flanker task have reported that response conflict is detected by the medial frontal cortex (MFC). As a conflict alert system, the MFC shows enhanced functional communication with task-related regions. Previous studies have revealed individual differences in functional connectivity during cognitive task performance. However, the mechanisms underlying these individual differences remain unclear. In the current study, electroencephalography (EEG) was recorded while 30 subjects performed a flanker task that was modified to exclude feature integration and contingency learning. The diffusion tensor imaging (DTI) data were collected the day before the EEG session. FCz-P3/4 theta phase synchronization was used to measure functional connectivity between the MFC and posterior parietal cortex (PPC). Hierarchical regression analyses were used to assess the relationship between MFC-PPC conflict-induced theta phase synchronization and white matter integrity in significant regions derived from tract-based spatial statistics (TBSS) analysis. As expected, MFC-PPC theta phase synchronization was significantly enhanced during conflict, suggesting a conflict-induced functional connectivity. However, these findings were only found in the right hemisphere, which may be related to the asymmetrical role of the bilateral PPC in response conflict processing. Furthermore, hierarchical regression analyses revealed that 44% of individual variability in FCz-P4 conflict-induced theta phase synchronization could be explained by variations in axial diffusivity (AD) in the genu of the corpus callosum (gCC). These results demonstrated that structural integrity in the gCC predicts conflict-induced functional connectivity between the MFC and right PPC. (C) 2017 IBRO. Published by Elsevier Ltd. All rights reserved.
资助项目	National Basic Research Program of China[2015CB856403][2014CB543203][2012CB518501] ; National Natural Science Foundation of China[81271644][81471811][81471738][61401346]
WOS研究方向	Neurosciences & Neurology
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
WOS记录号	WOS:000415967300016
状态	已发表
内容类型	期刊论文
源URL	[http://119.78.100.223/handle/2XXMBERH/32964]
专题	土木工程学院
通讯作者	Qin, Wei
作者单位	1.Xidian Univ, Sch Life Sci & Technol, Minist Educ, Engn Res Ctr Mol & Neuro Imaging, Xian 710071, Shaanxi, Peoples R China 2.Lanzhou Univ Technol, Sch Comp & Commun, Lanzhou 710050, Gansu, Peoples R China
推荐引用方式 GB/T 7714	Liu, Peng,Yu, Yang,Gao, Shudan,et al. Structural Integrity in the Genu of Corpus Callosum Predicts Conflict-induced Functional Connectivity Between Medial Frontal Cortex and Right Posterior Parietal Cortex[J]. NEUROSCIENCE,2017,366:162-171.
APA	Liu, Peng.,Yu, Yang.,Gao, Shudan.,Sun, Jinbo.,Yang, Xuejuan.,...&Qin, Wei.(2017).Structural Integrity in the Genu of Corpus Callosum Predicts Conflict-induced Functional Connectivity Between Medial Frontal Cortex and Right Posterior Parietal Cortex.NEUROSCIENCE,366,162-171.
MLA	Liu, Peng,et al."Structural Integrity in the Genu of Corpus Callosum Predicts Conflict-induced Functional Connectivity Between Medial Frontal Cortex and Right Posterior Parietal Cortex".NEUROSCIENCE 366(2017):162-171.