Enantioselective recognition of L/D-amino acids in the chiral nanochannels of a metal-organic framework

doi:10.1016/j.electacta.2021.139809

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	Enantioselective recognition of L/D-amino acids in the chiral nanochannels of a metal-organic framework
	Niu, Xiaohui; Yan, Simeng; Chen, Jinliang; Li, Hongxia; Wang, Kunjie
刊名	Electrochimica Acta
	2022-02-10
卷号	405
关键词	Amino acids Electrochemical sensors Metal-Organic Frameworks Organometallics Stereochemistry Chiral channels Chiral metal Chiral metal-organic framework Chiral properties d-Amino acids Electrochemical sensing Enantioselective recognition Ketjen black Metalorganic frameworks (MOFs) Nano channels
ISSN号	0013-4686
DOI	10.1016/j.electacta.2021.139809
英文摘要	Chiral metal-organic frameworks (MOF) have received extensive attention from researchers due to their chiral properties and potential applications in chiral-related fields. However, the construction of chiral metal-organic framework remains challenging due to the unpredictability of the synthesis process and the difficulty in keeping chirality during the growth of chiral MOF. Herein, a chiral MOF (D-His-ZIF-8) is reported for the construction of electrochemical sensing interface, which was synthesized via in-situ substitution of 2-methylimidazole on ZIF-8 by D-histidine (D-His). The introduction of Ketjen Black (KB) to the D-His-ZIF-8 sensing interface can improve its conductivity. The electrochemical recognition results show that KB/D-His-ZIF-8 has enantiodiscrimination ability for amino acids in voltammetry experiments. The best recognition efficiency is observed with Trp enantiomers. The recognition mechanism shows that the chiral nanochannel of D-His-ZIF-8 is conducive to the binding of L-amino acid, which will lead to the recognition of chiral molecules of different configurations. This research points to the possibility of developing further chiral recognition protocols based on D-His-ZIF-8, particularly with the suggested improvement in the preparation procedure of chiral MOF. © 2021 Elsevier Ltd
语种	英语
出版者	Elsevier Ltd
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/158027]
专题	石油化工学院
作者单位	College of Petrochemical Technology, Lanzhou University of Technology, Lanzhou; 730050, China
推荐引用方式 GB/T 7714	Niu, Xiaohui,Yan, Simeng,Chen, Jinliang,et al. Enantioselective recognition of L/D-amino acids in the chiral nanochannels of a metal-organic framework[J]. Electrochimica Acta,2022,405.
APA	Niu, Xiaohui,Yan, Simeng,Chen, Jinliang,Li, Hongxia,&Wang, Kunjie.(2022).Enantioselective recognition of L/D-amino acids in the chiral nanochannels of a metal-organic framework.Electrochimica Acta,405.
MLA	Niu, Xiaohui,et al."Enantioselective recognition of L/D-amino acids in the chiral nanochannels of a metal-organic framework".Electrochimica Acta 405(2022).