Fluorescent glutathione probe based on MnO2–Si quantum dots nanocomposite directly used for intracellular glutathione imaging

doi:10.1016/j.snb.2017.08.170

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	Fluorescent glutathione probe based on MnO2–Si quantum dots nanocomposite directly used for intracellular glutathione imaging
	Ma, Hong 1; Li, Xinran 1; Liu, Xiaoyu 1,2; Deng, Min 1; Wang, Xudong 1; Iqbal, Anam 1; Liu, Weisheng 1; Qin, Wenwu 1
刊名	Sensors and Actuators, B: Chemical
	2018-02-01
卷号	255 页码:1687-1693
关键词	Cell culture Cells Energy transfer Fluorescence Manganese oxide Nanocrystals Nanosheets Peptides Probes Silicon compounds Blue fluorescence Detection assay Fluorescent probes Glutathiones Intracellular imaging Low detection limit Si quantum dot Silicon quantum dots
ISSN号	09254005
DOI	10.1016/j.snb.2017.08.170
英文摘要	A highly sensitive glutathione probe based on silicon quantum dots (SiQDs) modified with MnO2 nanosheets has been developed. A strong reduction of the blue fluorescence of the SiQDs happened due to the surface energy transfer (SET) from SiQDs to the deposited MnO2. Fluorescence can be restored in the presence of glutathione on account of the MnO2 nanosheets are reduced. A fluorometric glutathione detection assay with a low detection limit (153 nM, at an S/N ratio of 3) can be designed via this method. It can be applied to directly determine GSH in living cells. A significant blue fluorescence image is produced in the cytosol of the cell and the fluorescence disappears while the cells treated with scavenger of GSH. © 2017 Elsevier B.V.
WOS研究方向	Chemistry ; Electrochemistry ; Instruments & Instrumentation
语种	英语
出版者	Elsevier B.V.
WOS记录号	WOS:000414319900064
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/114222]
专题	石油化工学院
作者单位	1.Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou; 730000, China; 2.College of Petrochemical Technology, Lanzhou University of Technology, Lanzhou; 730050, China
推荐引用方式 GB/T 7714	Ma, Hong,Li, Xinran,Liu, Xiaoyu,et al. Fluorescent glutathione probe based on MnO2–Si quantum dots nanocomposite directly used for intracellular glutathione imaging[J]. Sensors and Actuators, B: Chemical,2018,255:1687-1693.
APA	Ma, Hong.,Li, Xinran.,Liu, Xiaoyu.,Deng, Min.,Wang, Xudong.,...&Qin, Wenwu.(2018).Fluorescent glutathione probe based on MnO2–Si quantum dots nanocomposite directly used for intracellular glutathione imaging.Sensors and Actuators, B: Chemical,255,1687-1693.
MLA	Ma, Hong,et al."Fluorescent glutathione probe based on MnO2–Si quantum dots nanocomposite directly used for intracellular glutathione imaging".Sensors and Actuators, B: Chemical 255(2018):1687-1693.