Influence maximization problem aims to select a subset of k most influential nodes from a given network such that the spread of influence triggered by the seed set will be maximum. Greedy based algorithm sare time-consuming to approximate the expected influence spread o f given node set accurately and not well scalable to large-scale networks especially when the propagation probability is large. Conventional heuristics based on network topology or confined diffusion paths tend to suffer from the problem of low solution accuracy or huge memory cost. In this paper an effective discrete shuffled frog-leaping algorithm (DSFLA) is proposed to solve influence maximization problem in a more efficient way. Novel encoding mechanism and discrete evolutionary rules are conceived based on network topology structure for virtual frog population. To facilitate the global exploratory solution, a novel local exploitation mechanism combining deterministic and random walk strategies is put forward to improve the suboptimal meme of each memeplex in the frog population. The experimental results of influence spread in six real-world networks and statistical tests show that DSFLA perform s effectively in selecting targeted influential seed nodes for influence maximization and is superior than several state-of-the-art alternatives. (C) 2019 Elsevier B.V. All rights reserved.