Effect of Mg2+ on porous MgxCa3−x(PO4)2 composite scaffolds for bone engineering by 3D gel-printing

doi:10.1007/s10853-020-04590-x

	Effect of Mg2+ on porous MgxCa3−x(PO4)2 composite scaffolds for bone engineering by 3D gel-printing
	Shao, Huiping 3; Zhang, Yumeng 3; Lin, Tao 3; Peng, Jiang 1,4; Wang, Aiyuan 1,4; Yu, Fucheng 2; Zhang, Zhinan 3; Wang, Luhui 3
刊名	Journal of Materials Science
	2020-06-01
卷号	55 期号:18 页码:7870-7882
关键词	Metal ions Precipitation (chemical) Scaffolds Bone engineering Composite scaffolds Degradation behavior Improve performance Liquid phase precipitation Particle diameters Phosphate buffer salines Simple operation
ISSN号	00222461
DOI	10.1007/s10853-020-04590-x
英文摘要	In this paper, the precursors of MgxCa3−x(PO4)2 powders with different magnesium contents were first synthesized by a liquid-phase precipitation method with simple operation and easy control of the reaction process. And the MgxCa3−x(PO4)2 slurry was used to print porous scaffolds by 3D gel-printing (3DGP), and then the scaffolds were degreased and sintered to improve performance, which simplifies the process and saves costs. The effects of different magnesium ions (Mg2+) doping contents on the precursors were investigated. When Mg2+ doping content is 0, 5 mol%, 10 mol% and 30 mol%, the particle diameters of the precursors are, respectively, 44.51 μm, 41.91 μm, 38.38 μm and 31.93 μm. The effects of different Mg2+ doping amounts on the biological and mechanical properties of the scaffolds were studied. When the doping Mg2+ content is 0, 5 mol%, 10 mol% and 30 mol%, respectively, the porosity of the scaffolds is 72.11%, 70.26%, 69.83% and 65.15%, and the strength is 1.04 ± 0.01 MPa, 0.73 ± 0.17 MPa, 0.23 ± 0.01 MPa and 1.89 ± 0.21 MPa, respectively. The degradation behavior was observed when the scaffolds were immersed in phosphate buffer saline for 8 weeks, which indicate that MgxCa3−x(PO4)2 composite scaffolds are expected to be more widely used in the field of bone defect repairing. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.
WOS研究方向	Materials Science
语种	英语
出版者	Springer
WOS记录号	WOS:000521902400004
内容类型	期刊论文
源URL	[http://ir.lut.edu.cn/handle/2XXMBERH/115531]
专题	材料科学与工程学院
作者单位	1.Institute of Orthopedics, Chinese PLA General Hospital, Beijing; 100853, China; 2.School of Material Science and Engineering, Lanzhou University of Technology, Lanzhou, China 3.Institute for Advanced Materials and Technology, University of Science and Technology Beijing, Beijing; 100083, China; 4.Key Laboratory of Regenerative Medicine in Orthopedics, Key Laboratory of Musculoskeletal Trauma & War Injuries PLA, Beijing; 100853, China;
推荐引用方式 GB/T 7714	Shao, Huiping,Zhang, Yumeng,Lin, Tao,et al. Effect of Mg2+ on porous MgxCa3−x(PO4)2 composite scaffolds for bone engineering by 3D gel-printing[J]. Journal of Materials Science,2020,55(18):7870-7882.
APA	Shao, Huiping.,Zhang, Yumeng.,Lin, Tao.,Peng, Jiang.,Wang, Aiyuan.,...&Wang, Luhui.(2020).Effect of Mg2+ on porous MgxCa3−x(PO4)2 composite scaffolds for bone engineering by 3D gel-printing.Journal of Materials Science,55(18),7870-7882.
MLA	Shao, Huiping,et al."Effect of Mg2+ on porous MgxCa3−x(PO4)2 composite scaffolds for bone engineering by 3D gel-printing".Journal of Materials Science 55.18(2020):7870-7882.