Cistanche polysaccharide (CDPS)/polylactic acid (PLA) scaffolds based coaxial electrospinning for vascular tissue engineering

doi:10.1080/00914037.2015.1055629

	Cistanche polysaccharide (CDPS)/polylactic acid (PLA) scaffolds based coaxial electrospinning for vascular tissue engineering
	Zhang Weijie 2; Chen Zhuo 2; Ma Sujuan 2; Wang Yonggang 2; Zhang Fei 2; Wang Keyi 2; Yang Chenguang 2; Pu Xiuying 2; Ma Jianzhong 2; Wang Yuli 2
刊名	INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
	2016
卷号	65 期号:1 页码:38-46
关键词	CDPS cistanche polysaccharide coaxial electrospinning vascular tissue engineering
ISSN号	0091-4037
DOI	10.1080/00914037.2015.1055629
英文摘要	High rate of platelet adhesion and limited biocompatibility were regarded as the chief weaknesses of vascular tissue engineering scaffolds. The objective of this research was to overcome these drawbacks by ultilizing coaxial electrospinning to combine CDPS with PLA. CDPS and PLA were located at the inner and external layer respectively so that a "core-sheath" structure was formed. The properties of scaffolds were tested by methods such as mechanical testing, MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay and subcutaneous transplantation. Compared to natural tissues, CDPS/PLA coaxial scaffolds showed excellent biomechanic properties and hemocompatibility so that CDPS owned good potentiality in vascular tissue engineering.
资助项目	Lanzhou Administration of Science and Technology[2012-2-68]
WOS研究方向	Materials Science ; Polymer Science
语种	英语
出版者	TAYLOR & FRANCIS AS
WOS记录号	WOS:000362723600005
状态	已发表
内容类型	期刊论文
源URL	[http://119.78.100.223/handle/2XXMBERH/33867]
专题	生命科学与工程学院材料科学与工程学院党委组织部（党校、帮扶办）
通讯作者	Zhang Weijie
作者单位	1.S China Normal Univ, Sch Life Sci, Guangzhou, Guangdong, Peoples R China 2.Lanzhou Univ Technol, Sch Life Sci & Engn, Gansu Educ Dept, Key Lab Screening Evaluat & Adv Proc TCM & Tibeta, Lanzhou 730050, Peoples R China 3.Lanzhou Univ Technol, Sch Mat Sci & Engn, Lanzhou 730050, Peoples R China
推荐引用方式 GB/T 7714	Zhang Weijie,Chen Zhuo,Ma Sujuan,et al. Cistanche polysaccharide (CDPS)/polylactic acid (PLA) scaffolds based coaxial electrospinning for vascular tissue engineering[J]. INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS,2016,65(1):38-46.
APA	Zhang Weijie.,Chen Zhuo.,Ma Sujuan.,Wang Yonggang.,Zhang Fei.,...&Kuang Yanbei.(2016).Cistanche polysaccharide (CDPS)/polylactic acid (PLA) scaffolds based coaxial electrospinning for vascular tissue engineering.INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS,65(1),38-46.
MLA	Zhang Weijie,et al."Cistanche polysaccharide (CDPS)/polylactic acid (PLA) scaffolds based coaxial electrospinning for vascular tissue engineering".INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS 65.1(2016):38-46.