Mechanisms of protein fouling in microfiltration. II. Adsorption and deposition of proteins on microfiltration membranes

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	Mechanisms of protein fouling in microfiltration. II. Adsorption and deposition of proteins on microfiltration membranes
	Zhang, JD; Cai, ZL; Cong, W; Su, ZG; Fan, PY
刊名	SEPARATION SCIENCE AND TECHNOLOGY
	2002
卷号	37 期号:13 页码:3039-3051
关键词	microfiltration protein fouling adsorption deposition
ISSN号	0149-6395
其他题名	Sep. Sci. Technol.
中文摘要	Adsorption and deposition of proteins in/on membranes were two main mechanisms of protein fouling in microfiltration. To distinguish the two mechanisms, adsorption and deposition were studied under both static and filtration conditions. The results demonstrated that under static conditions, adsorption had an equilibrium and the equilibrium amount of adsorption was almost constant even in solutions with different concentrations. The maximum adsorption occurred at isoelectric point pH value, and the amount of protein absorbed was similar to that of monolayer type adsorption. In actual microfiltration, adsorption and deposition of proteins occur simultaneously and the adsorption has an equilibrium with adsorption values similar to that of static adsorption. The amount of protein that deposited onto the membranes was simply proportional to filtration volume of the solution. The result can be described by a mathematical model.
英文摘要	Adsorption and deposition of proteins in/on membranes were two main mechanisms of protein fouling in microfiltration. To distinguish the two mechanisms, adsorption and deposition were studied under both static and filtration conditions. The results demonstrated that under static conditions, adsorption had an equilibrium and the equilibrium amount of adsorption was almost constant even in solutions with different concentrations. The maximum adsorption occurred at isoelectric point pH value, and the amount of protein absorbed was similar to that of monolayer type adsorption. In actual microfiltration, adsorption and deposition of proteins occur simultaneously and the adsorption has an equilibrium with adsorption values similar to that of static adsorption. The amount of protein that deposited onto the membranes was simply proportional to filtration volume of the solution. The result can be described by a mathematical model.
WOS标题词	Science & Technology ; Physical Sciences ; Technology
类目[WOS]	Chemistry, Multidisciplinary ; Engineering, Chemical
研究领域[WOS]	Chemistry ; Engineering
关键词[WOS]	INTERMOLECULAR FORCES ; FILTRATION ; FLUX ; ULTRAFILTRATION ; RELEVANCE
收录类别	SCI
原文出处	://WOS:000178523600005
语种	英语
WOS记录号	WOS:000178523600005
公开日期	2013-11-12
内容类型	期刊论文
版本	出版稿
源URL	[http://ir.ipe.ac.cn/handle/122111/5680]
专题	过程工程研究所_研究所（批量导入）
作者单位	Chinese Acad Sci, Inst Proc Engn, Natl Lab Biochem Engn China, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Zhang, JD,Cai, ZL,Cong, W,et al. Mechanisms of protein fouling in microfiltration. II. Adsorption and deposition of proteins on microfiltration membranes[J]. SEPARATION SCIENCE AND TECHNOLOGY,2002,37(13):3039-3051.
APA	Zhang, JD,Cai, ZL,Cong, W,Su, ZG,&Fan, PY.(2002).Mechanisms of protein fouling in microfiltration. II. Adsorption and deposition of proteins on microfiltration membranes.SEPARATION SCIENCE AND TECHNOLOGY,37(13),3039-3051.
MLA	Zhang, JD,et al."Mechanisms of protein fouling in microfiltration. II. Adsorption and deposition of proteins on microfiltration membranes".SEPARATION SCIENCE AND TECHNOLOGY 37.13(2002):3039-3051.