Total synthesis of (+/-)-brazilin and formal synthesis of (+/-)-brazilein, (+/-)-brazilide A using m-CPBA

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Total synthesis of (+/-)-brazilin and formal synthesis of (+/-)-brazilein, (+/-)-brazilide A using m-CPBA
	Li, Liang-Qun 1,2; Li, Ming-Ming 1; Wang, Kou 3; Qin, Hong-Bo1
刊名	TETRAHEDRON LETTERS
	2013-11-06
卷号	54 期号:45 页码:6029-6031
关键词	Total synthesis Brazilin Brazilein Brazilide A m-CPBA
ISSN号	0040-4039
通讯作者	Qin, HB (reprint author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China.,qinhongbo@mail.kib.ac.cn
英文摘要	Total synthesis of (+/-)-brazilin has been accomplished. m-CPBA epoxidation of allyl alcohol 10 and epoxy opening reaction mediated by m-chlorobenzoic acid, formed in situ as a byproduct, gave advanced intermediate diol 14. O-alkylation and cyclization gave phenol 6 which enabled the formal synthesis of (+/-)-brazilein and (+/-)-brazilide A. (C) 2013 Elsevier Ltd. All rights reserved.
学科主题	Chemistry, Organic
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Chemistry, Organic
研究领域[WOS]	Chemistry
关键词[WOS]	CAESALPINIA-SAPPAN ; BRAZILEIN ; ANALOGS ; CELLS
收录类别	SCI ; IC ; CCR
资助信息	National Natural Science Foundation of China [21372229]
语种	英语
WOS记录号	WOS:000325736300023
公开日期	2013-11-12
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/17276]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Kunming Med Univ, Yunnan Key Lab Pharmacol Nat Prod, Sch Pharmaceut Sci, Kunming 650500, Peoples R China
推荐引用方式 GB/T 7714	Li, Liang-Qun,Li, Ming-Ming,Wang, Kou,et al. Total synthesis of (+/-)-brazilin and formal synthesis of (+/-)-brazilein, (+/-)-brazilide A using m-CPBA[J]. TETRAHEDRON LETTERS,2013,54(45):6029-6031.
APA	Li, Liang-Qun,Li, Ming-Ming,Wang, Kou,&Qin, Hong-Bo.(2013).Total synthesis of (+/-)-brazilin and formal synthesis of (+/-)-brazilein, (+/-)-brazilide A using m-CPBA.TETRAHEDRON LETTERS,54(45),6029-6031.
MLA	Li, Liang-Qun,et al."Total synthesis of (+/-)-brazilin and formal synthesis of (+/-)-brazilein, (+/-)-brazilide A using m-CPBA".TETRAHEDRON LETTERS 54.45(2013):6029-6031.