Simultaneous Determination of Sulfonamides Antibiotics in Environmental Water and Seafood Samples Using Ultrasonic-Assisted Dispersive Liquid-Liquid Microextraction Coupled with High Performance Liquid Chromatography

doi:10.3390/molecules27072160

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Simultaneous Determination of Sulfonamides Antibiotics in Environmental Water and Seafood Samples Using Ultrasonic-Assisted Dispersive Liquid-Liquid Microextraction Coupled with High Performance Liquid Chromatography
	Wang, Yixiao 3,4; Li, Jinhua 2,3,4; Ji, Ling 1; Chen, Lingxin 2,4
刊名	MOLECULES
	2022-04-01
卷号	27 期号:7 页码:16
关键词	dispersive liquid-liquid microextraction ultrasonic-assisted sulfonamides antibiotics environmental water seafood samples
DOI	10.3390/molecules27072160
通讯作者	Li, Jinhua(jhli@yic.ac.cn)
英文摘要	The residues and abuse of antibiotics have seriously endangered ecological balance and human health; meanwhile, antibiotics determination is very difficult because of their low levels and multiple categories in complicated matrices. Appropriate sample pretreatment is usually imperative to enrich (ultra)trace antibiotics and eliminate matrix interference prior to chromatographic analysis. Dispersive liquid-liquid microextraction (DLLME) has become an ideal pretreatment technique owing to its simplicity, effectiveness, low-consumption, etc. In this work, an ultrasonic-assisted DLLME (UA-DLLME) was developed for the simultaneous extraction of seven sulfonamides (SAs) antibiotics in environmental water and seafood samples coupled with HPLC-DAD determination. Several parameters affecting UA-DLLME efficiency were systematically optimized, and consequently the SAs were separated and detected within 14.5 min. The obtained limits of detection (LODs) and limits of quantification (LOQs) ranged from 0.7-7.8 mu g/L and 2.4-26.0 mu g/L for three water samples (seawater, aquaculture wastewater and lake water) and two seafood samples (pomfrets and shrimps). High recoveries (80.0-116.0%) with low relative standard deviations (0.1-8.1%) were achieved for all the tested samples at three spiked levels. Notably, sulfadimethoxine was found at 24.49 mu g/L in one seawater sample. The facile, robust and benign DLLME-HPLC method demonstrated promising perspectives for multiresidue analysis of antibiotics.
WOS关键词	MASS-SPECTROMETRY ; RESISTANCE GENES ; EXTRACTION ; AQUACULTURE ; RESIDUES ; ESTUARY
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
WOS记录号	WOS:000781408400001
资助机构	National Natural Science Foundation of China ; Science and Technology Innovation Development Plan of Yantai City of China ; Natural Science Foundation of Shandong Province of China ; Taishan Scholar Project Special Funding
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/31381]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
通讯作者	Li, Jinhua
作者单位	1.State Ocean Adm, Yantai Ocean Environm Monitoring Cent Stn, Yantai 264006, Peoples R China 2.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, Sch Source & Environm, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Res Ctr Coastal Environm Engn & Technol Shandong, Shandong Key Lab Coastal Environm Proc, Yantai Inst Coastal Zone Res,CAS Key Lab Coastal, Yantai 264003, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yixiao,Li, Jinhua,Ji, Ling,et al. Simultaneous Determination of Sulfonamides Antibiotics in Environmental Water and Seafood Samples Using Ultrasonic-Assisted Dispersive Liquid-Liquid Microextraction Coupled with High Performance Liquid Chromatography[J]. MOLECULES,2022,27(7):16.
APA	Wang, Yixiao,Li, Jinhua,Ji, Ling,&Chen, Lingxin.(2022).Simultaneous Determination of Sulfonamides Antibiotics in Environmental Water and Seafood Samples Using Ultrasonic-Assisted Dispersive Liquid-Liquid Microextraction Coupled with High Performance Liquid Chromatography.MOLECULES,27(7),16.
MLA	Wang, Yixiao,et al."Simultaneous Determination of Sulfonamides Antibiotics in Environmental Water and Seafood Samples Using Ultrasonic-Assisted Dispersive Liquid-Liquid Microextraction Coupled with High Performance Liquid Chromatography".MOLECULES 27.7(2022):16.