Assessing the Effect of Modified Clay on the Toxicity of Karenia mikimotoi Using Marine Medaka (Oryzias melastigma) as a Model Organism

doi:10.3390/toxics10030105

CORC > 海洋研究所 > 中国科学院海洋研究所 > 海洋生态与环境科学重点实验室

	Assessing the Effect of Modified Clay on the Toxicity of Karenia mikimotoi Using Marine Medaka (Oryzias melastigma) as a Model Organism
	Zhang, Peipei 1,2,3,4; Song, Xiuxian 1,2,3,4; Zhang, Yue 1,3; Zhu, Jianan 1,2,3; Shen, Huihui 1,2,3,4; Yu, Zhiming 1,2,3,4
刊名	TOXICS
	2022-03-01
卷号	10 期号:3 页码:19
关键词	modified clay Karenia mikimotoi harmful algal bloom marine medaka marine toxicity tests
DOI	10.3390/toxics10030105
通讯作者	Song, Xiuxian(songxx@qdio.ac.cn)
英文摘要	Blooms of the toxic dinoflagellate Karenia mikimotoi could threaten the survival of marine life, and modified clay (MC) is considered a promising method for the control of harmful algal blooms. Here, using marine medaka as the model organism, the toxicity of K. mikimotoi before and after MC disposal was investigated. The results showed that only a certain density of intact K. mikimotoi cells could cause obvious damage to fish gills and lead to rapid death. A systematic analysis of morphology, physiology, and molecular biology parameters revealed that the fish gills exhibited structural damage, oxidative damage, osmotic regulation impairment, immune response activation, and signal transduction enhancement. MC can flocculate K. mikimotoi rapidly in water and reduce its toxicity by reducing the density of intact algae cells and hemolytic toxicity. The results indicate that MC is an effective and safe method for controlling K. mikimotoi blooms.
资助项目	National Natural Science Foundation of China[41976148] ; Key R&D project of Shandong Province[2019JZZY010808] ; Taishan Program of Shandong Province of 2019
WOS研究方向	Environmental Sciences & Ecology ; Toxicology
语种	英语
出版者	MDPI
WOS记录号	WOS:000776410900001
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/178645]
专题	海洋研究所_海洋生态与环境科学重点实验室
通讯作者	Song, Xiuxian
作者单位	1.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266000, Peoples R China 2.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266000, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Ecol & Environm Sci, Qingdao 266000, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Peipei,Song, Xiuxian,Zhang, Yue,et al. Assessing the Effect of Modified Clay on the Toxicity of Karenia mikimotoi Using Marine Medaka (Oryzias melastigma) as a Model Organism[J]. TOXICS,2022,10(3):19.
APA	Zhang, Peipei,Song, Xiuxian,Zhang, Yue,Zhu, Jianan,Shen, Huihui,&Yu, Zhiming.(2022).Assessing the Effect of Modified Clay on the Toxicity of Karenia mikimotoi Using Marine Medaka (Oryzias melastigma) as a Model Organism.TOXICS,10(3),19.
MLA	Zhang, Peipei,et al."Assessing the Effect of Modified Clay on the Toxicity of Karenia mikimotoi Using Marine Medaka (Oryzias melastigma) as a Model Organism".TOXICS 10.3(2022):19.