Effect of phenolic compound-protein covalent conjugation on the physicochemical, anti-inflammatory, and antioxidant activities of silk sericin | |
Omar, A (Omar, Adil) [1] , [2]; Arken, A (Arken, Amina) [1] , [2]; Wali, A (Wali, Ahmidin) [1]; Gao, YH (Gao, Yanhua) [1]; Aisa, HA (Aisa, Haji Akber) [1]; Yili, A (Yili, Abulimiti) [1] | |
刊名 | PROCESS BIOCHEMISTRY |
2022 | |
卷号 | 117期号:6页码:101-109 |
关键词 | SericinPhenolic compoundsCovalent interactionAntioxidantsAnti-inflammatory |
ISSN号 | 1359-5113 |
DOI | 10.1016/j.procbio.2022.03.008 |
英文摘要 | Sericin, as an inexpensive byproduct of the silk industry, has drawn increasing attention due to its good biocompatibility and various bioactivities. Covalent interactions between proteins and phenolic compounds are ubiquitous and can affect the functional properties of proteins, but little is known about the interactions between sericin and phenolic compounds. In our research, hydroquinone and pyrogallol were selected as model phenolic compounds to investigate the interaction between sericin and phenolic compounds. UV spectroscopy and SECHPLC confirmed that sericin and oxidized phenolic compounds formed conjugates, which were primarily the result of covalent interactions. The covalent binding of phenolic compounds changed the secondary structure and thermal behavior of sericin and increased its surface hydrophobicity. The covalent interaction had a positive effect on the emulsifying activity of sericin. Likewise, the antioxidant activity and anti-inflammatory activity of sericin were enhanced in the presence of phenolic compounds. Sericin-phenolic conjugates would be used as multifunctional ingredients in cosmetics, food, and other industries due to their improved emulsifying, antioxidant, and anti-inflammatory properties. |
WOS记录号 | WOS:000806790000002 |
内容类型 | 期刊论文 |
源URL | [http://ir.xjipc.cas.cn/handle/365002/8392] |
专题 | 新疆理化技术研究所_资源化学研究室 |
通讯作者 | Yili, A (Yili, Abulimiti) [1] |
作者单位 | 1.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Beijing South Rd 40-1, Urumqi 830011, Peoples R China |
推荐引用方式 GB/T 7714 | Omar, A ,Arken, A ,Wali, A ,et al. Effect of phenolic compound-protein covalent conjugation on the physicochemical, anti-inflammatory, and antioxidant activities of silk sericin[J]. PROCESS BIOCHEMISTRY,2022,117(6):101-109. |
APA | Omar, A ,Arken, A ,Wali, A ,Gao, YH ,Aisa, HA ,&Yili, A .(2022).Effect of phenolic compound-protein covalent conjugation on the physicochemical, anti-inflammatory, and antioxidant activities of silk sericin.PROCESS BIOCHEMISTRY,117(6),101-109. |
MLA | Omar, A ,et al."Effect of phenolic compound-protein covalent conjugation on the physicochemical, anti-inflammatory, and antioxidant activities of silk sericin".PROCESS BIOCHEMISTRY 117.6(2022):101-109. |
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