A self-driven microfluidic surface-enhanced Raman scattering device for Hg2+ detection fabricated by femtosecond laser
X. Y. Li,G. Yuan,W. L. Yu,J. Xing,Y. T. Zou,C. Zhao,W. C. Kong,Z. Yu and C. L. Guo
刊名Lab on a Chip
2020
卷号20期号:2页码:414-423
ISSN号1473-0197
DOI10.1039/c9lc00883g
英文摘要In this paper, we proposed a novel approach for rapid and flexible fabrication of self-driven microfluidic surface enhanced Raman scattering (SERS) chips for quantitative analysis of Hg2+ by femtosecond laser direct writing. In contrast to traditional microfluidic chips, the microchannels of the device can drive a liquid sample flow without external driving force. The sample flow speed is tunable since the wettability and capillarity properties of the channels, which depend on the roughness and the inner diameter of the microchannels, can be controlled by optimizing the laser processing parameters. The SERS active detection sites, which exhibit high enhancement effects and fine reproducibility, were integrated through the femtosecond laser-induced periodic surface structures (LIPSS), followed by 30 nm Ag deposition. The SERS performance of the as-prepared microfluidic SERS detection chip was studied with R6G as probe molecules. The quantitative analysis of Hg2+ was realized by simply injecting the Hg2+ sample and the probe molecules R6G from the two inlets, separately, and collecting the SERS signal at the detection site. The lowest detection limit for Hg2+ is 10(-9) M. It should be mentioned that this study is not only limited to Hg2+ quantitative analysis, but is also mainly aimed to develop a new technique for the design and fabrication of novel self-driven microfluidic devices depending on practical application requirements.
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语种英语
内容类型期刊论文
源URL[http://ir.ciomp.ac.cn/handle/181722/64873]  
专题中国科学院长春光学精密机械与物理研究所
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X. Y. Li,G. Yuan,W. L. Yu,J. Xing,Y. T. Zou,C. Zhao,W. C. Kong,Z. Yu and C. L. Guo. A self-driven microfluidic surface-enhanced Raman scattering device for Hg2+ detection fabricated by femtosecond laser[J]. Lab on a Chip,2020,20(2):414-423.
APA X. Y. Li,G. Yuan,W. L. Yu,J. Xing,Y. T. Zou,C. Zhao,W. C. Kong,Z. Yu and C. L. Guo.(2020).A self-driven microfluidic surface-enhanced Raman scattering device for Hg2+ detection fabricated by femtosecond laser.Lab on a Chip,20(2),414-423.
MLA X. Y. Li,G. Yuan,W. L. Yu,J. Xing,Y. T. Zou,C. Zhao,W. C. Kong,Z. Yu and C. L. Guo."A self-driven microfluidic surface-enhanced Raman scattering device for Hg2+ detection fabricated by femtosecond laser".Lab on a Chip 20.2(2020):414-423.
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