River pollution is becoming a serious problem worldwide. A field-scale experiment was undertaken to remediate a heavily polluted river using a combined engineering approach of aeration, microorganisms, biological aerated filtration, artificial biofilms and ecological floating beds. Prior to remediation, the river water was black, anoxic and highly sulfidic. With remediation, the chemical oxygen demand decreased from similar to 250 to similar to 50 mg L-1, NH4+-N decreased from similar to 27 to similar to 4 mg L-1, sulfide decreased from similar to 3 to similar to 0.3 mg L-1, and total suspended solids decreased from similar to 270 to similar to 40 mg L-1. At the same time, dissolved oxygen increased from similar to 0.1 to similar to 3.5 mg L-1, and water clarity increased from similar to 6 to similar to 40 cm. Furthermore, the unpleasant odor emanating from the polluted river was also stopped, and local farmers have begun using the water for irrigation. This field-scale experiment thus indicates the potential usefulness of this combined engineering approach to remediate heavily polluted rivers.