Electrochemical Detection of Insulin Based on Screen Printed Electrode Modified by Nickel Hydroxide

CORC > 沈阳自动化研究所 > 中国科学院沈阳自动化研究所 > 机器人学研究室

	Electrochemical Detection of Insulin Based on Screen Printed Electrode Modified by Nickel Hydroxide
	Zhang, Hongyu 3; Zhan ZK(詹志坤)3; Zhao YL(赵玉良)1; Sha XP(沙晓鹏)1; Yu, Xiaodong 1; Sun, Hui 1; Gu, Lijia 1; Liu, Jiali 1; Liu LQ(刘连庆)2
	2018
会议日期	December 5-7, 2018
会议地点	Shenzhen, China
关键词	Insulin detection Nickel hydroxide, Screen Printed Electrode Electrochemical Detection
页码	55-59
英文摘要	This paper reports a novel electrochemical method for the detection of insulin in ultra-pure water. A screen printed electrode (SPE) modified by Nickel hydroxide was used as the working electrode, one with good activity of electro-catalytic oxidation-reduction for insulin. The SPE was modified by Nickel hydroxide using the electrodeposition method. The results showed that Nickel hydroxide was homogeneously electrodeposited on the surface of the working electrode. A coin-size electrolytic tank was fabricated with PDMS, which only requires 0.3ml of sample for the detection. The concentration of insulin was analyzed using the methods of Cyclic voltammetry (CV), Electrochemical impedance spectroscopy (EIS) and Chronoamperometry (i-t). The Nickel hydroxide used for detecting insulin showed good analytical characteristics, such as a high sensitivity of \pmb{14.797\mu} \mathbf{A}\bullet\pmb{\mu} \mathbf{M}^{\pmb{-1}}, a good linear detection range of \pmb{100}\mathbf{nM}\pmb{-5\mu} \mathbf{M}, and a low detection limit of 93nM. This nickel hydroxide modified SPE electrode has a much smaller size and is easier to fabricate than traditional electrodes, making it a much more promising candidate for an insulin sensor.
产权排序	3
会议录	Proceedings of the 1st IEEE International Conference on Micro/Nano Sensors for AI, Healthcare and Robotics
会议录出版者	IEEE
会议录出版地	New York
语种	英语
ISBN号	978-1-5386-9408-4
WOS记录号	WOS:000470204100012
内容类型	会议论文
源URL	[http://ir.sia.cn/handle/173321/24696]
专题	沈阳自动化研究所_机器人学研究室
通讯作者	Zhan ZK(詹志坤); Zhao YL(赵玉良)
作者单位	1.School of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066004, China 2.State Key Laboratory of Robotics, Shenyang Institute of Automation, Chinese Academy of Sciences, China 3.Key Lab of Industrial Computer Control Engineering of Hebei Province, School of Electrical Engineering, Yanshan University, Qinhuangdao 066004, China
推荐引用方式 GB/T 7714	Zhang, Hongyu,Zhan ZK,Zhao YL,et al. Electrochemical Detection of Insulin Based on Screen Printed Electrode Modified by Nickel Hydroxide[C]. 见:. Shenzhen, China. December 5-7, 2018.